Evidence map›Paper›PMID 40519462›Full record

ArticleCureus2025

A Rare Presentation of Hypocalcaemia-Induced Seizure Secondary to Late-Onset Post-Thyroidectomy Complication.

Yameen Hamid, Md Al Amin Sarkar, Sudip Karmaker, Samarea Nowrin, S M Amanat Ullah

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yameen HamidStem Cell and Translational Neurology, University of Edinburgh, Edinburgh, GBR.
Md Al Amin SarkarAcute Medicine, Medway NHS Foundation Trust, Gillingham, GBR.
Sudip KarmakerAcute Medicine, Medway NHS Foundation Trust, Gillingham, GBR.
Samarea NowrinGeneral Practice, Maidstone and Tunbridge Wells NHS Trust, Maidstone, GBR.
S M Amanat UllahAcute Medicine, Medway NHS Foundation Trust, Gillingham, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a rare case of late-onset hypocalcaemia presenting with seizure in a female patient, occurring approximately 25 years after a total thyroidectomy. Initial investigations ruled out intracranial pathology, and biochemical analysis confirmed severe hypocalcaemia. The patient responded to intravenous calcium gluconate infusion, with subsequent stabilisation on oral calcium therapy. Notably, the patient had been non-compliant with long-term calcium supplementation. This report underscores that chronic hypocalcaemia can manifest with acute neurological symptoms such as seizures and highlights the importance of long-term follow-up for post-thyroidectomy patients.

Indexed as

endocrinologyhypocalcaemia induced seizurehypocalcaemia without hypoparathyroidismlate-onset hypocalcaemiapost-thyroidectomy complication

Identifiers

PMID40519462
PMCPMC12166952

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.