Evidence map›Paper›PMID 40519455›Full record

ArticleCureus2025

Artificial Intelligence-Driven Telehealth Framework for Detecting Nystagmus.

Harshal Sanghvi, Ali A Danesh, Jillene Moxam, Sandeep K Reddy, Gurnoor S Gill, B Sue Graves, Sajeel Chowdhary, Kakarla Chalam, Shailesh Gupta, Abhijit S Pandya

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Harshal SanghviDepartment of Information Technology and Operations Management, College of Business, Florida Atlantic University, Boca Raton, USA.
Ali A DaneshDepartment of Communication Sciences and Disorders, Florida Atlantic University, Boca Raton, USA.
Jillene MoxamDepartment of Technology and Clinical Trials, Advanced Research, Deerfield Beach, USA.
Sandeep K ReddyDepartment of Electrical Engineering and Computer Science, Florida Atlantic University, Boca Raton, USA.
Gurnoor S GillDepartment of Medicine, Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, USA.
B Sue GravesDepartment of Exercise Science and Health Promotion, Florida Atlantic University, Boca Raton, USA.
Sajeel ChowdharyDepartment of Neurology, Baptist Health Medical Center, Boca Raton, USA.
Kakarla ChalamDepartment of Ophthalmology, Loma Linda University Medical Center, Loma Linda, USA.
Shailesh GuptaDepartment of Ophthalmology, Broward Health North, Deerfield Beach, USA.
Abhijit S PandyaDepartment of Electrical Engineering and Computer Science, Florida Atlantic University, Boca Raton, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study reports the implementation of a proof-of-concept, artificial intelligence (AI)-driven clinical decision support system for detecting nystagmus. The system collects and analyzes real-time clinical data to assist in diagnosing, demonstrating its potential for integration into telemedicine platforms. Patients may benefit from the system's convenience, reduced need for travel and associated costs, and increased flexibility and increased flexibility through both in-person and virtual applications.

methodsA bedside clinical test revealed vertigo during rightward body movement, and the patient was referred for videonystagmography (VNG). The VNG showed normal central ocular findings. During the right Dix-Hallpike maneuver, the patient demonstrated rotatory nystagmus accompanied by vertigo. Caloric tests revealed symmetric responses, with no evidence of unilateral or bilateral weakness. A cloud-based deep learning framework was developed and trained to track eye movements and detect 468 distinct facial landmarks in real time. Ten subjects participated in this study.

resultsThe slow-phase velocity (SPV) value was verified for statistical significance using both VNG machine-generated graphs and clinician assessment. The average SPV was compared to the value generated by the VNG machine. The calculated statistical values were as follows: p < 0.05, a mean squared error of 0.00459, and a correction error of ±4.8%.

conclusionThis deep learning model demonstrates the potential to provide diagnostic consultation to individuals in remote locations. To some extent, it may supplement or partially replace traditional methods such as VNG. Ongoing advancements in machine learning within medicine will enhance the ability to diagnose patients, facilitate appropriate specialist referrals, and support physicians in post-treatment follow-up. As this was a proof-of-concept pilot study, further research with a larger sample size is warranted.

Indexed as

diagnostic testingevaluation for telehealthnystagmusophthalmic researchophthalmology

Identifiers

PMID40519455
PMCPMC12162396

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.