ArticleCureus2025
Low-Intensity Pulsed Ultrasound in Patients With Atherosclerotic Peripheral Arterial Disease: A Pilot Study and Randomized Double-Blind Placebo-Controlled Trial.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Low-intensity ultrasound induces angiogenesis by activating endothelial integrin signaling in male mice.Physiological reports · 2026Article
- Low-Intensity Pulsed Ultrasound Therapy for Patients With Rutherford Stage 4 Peripheral Arterial Disease.JACC. Case reports · 2025Article
- Effects of low-intensity pulsed ultrasound on muscle mass and Fndc5 mRNA expression in aged male mice.Biogerontology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction Low-intensity pulsed ultrasound (LIPUS) influences myogenesis, osteogenesis, and angiogenesis. The purpose of this study was to evaluate the effect of LIPUS on symptoms in patients with atherosclerotic peripheral arterial disease (PAD). Methods This pilot study was a double-blinded, placebo-controlled, and randomized study for investigation of LIPUS treatment in patients with atherosclerotic PAD. Thirteen subjects received active LIPUS devices, and another 13 control subjects received inactive LIPUS devices for a 24-week period. The outcomes of symptoms, along with visual analog score (VAS), ankle-brachial index (ABI), transcutaneous oxygen pressure (TcPO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.