ArticleCureus2025
Papillary Thyroid Carcinoma Arising From a Thyroglossal Duct Cyst: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Papillary carcinoma in thyroglossal duct cyst: A case report.Radiology case reports · 2026Article
- Thyroglossal Duct Cyst in a Tertiary Hospital in Kaduna: A Retrospective Review.Nigerian medical journal : journal of the Nigeria Medical AssociationArticle
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The thyroglossal duct is an epithelial tract that connects the foramen cecum to the thyroid gland and typically regresses during embryonic development. When remnants of this duct persist, they can form cysts known as thyroglossal duct cysts. Although generally benign, these cysts can undergo malignant transformation, most commonly into papillary carcinoma. Here, we report a case of thyroglossal duct carcinoma in a 22-year-old woman who presented with submental swelling. Imaging revealed features suggestive of malignancy, including microcalcifications and irregular solid components within the cyst. However, multiple fine-needle aspiration cytology (FNAC) procedures failed to detect malignancy. Based on the imaging findings, the patient underwent Sistrunk surgery, and postoperative histopathological analysis confirmed papillary carcinoma arising from a thyroglossal duct cyst. The diagnosis was challenging due to the tumor's localization within a limited area of the cyst. One year after surgery, the patient showed no signs of recurrence or metastasis. This case highlights the importance of considering malignancy in midline neck masses, even when FNAC results are inconclusive, and underscores the role of early diagnosis and appropriate surgical intervention.
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