ArticleCureus2025
Drug-Induced Sleep Endoscopy for Targeted Sleep Surgery in Pediatric Patients.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThis study aims to evaluate the efficacy of drug-induced sleep endoscopy (DISE)-targeted surgery to identify the locations of obstruction and to determine how DISE findings influence whether the standard of care surgery, adenotonsillectomy, is performed.
methodsThis prospective cohort study was done at an academic children's hospital. All patients (n = 42) underwent polysomnography. DISE was performed to evaluate tonsil and adenoid size, Yellon tongue base, lateral pharyngeal wall (LPW) collapse, and signs of laryngomalacia. Surgery was performed based on the most prominent locations of obstruction. Pre-operative and post-operative University of Michigan Pediatric Sleep Questionnaire (UMPSQ) was given to determine the likelihood of residual OSA.
resultsSurgeries included tonsillectomy, adenoidectomy, lingual tonsillectomy, laryngeal cleft repair, supraglottoplasty, and turbinate reduction. Patients had improvement in the UMPSQ score from 13.36 ± 3.67 to 5.68 ± 3.46 (P=0.05). Those who underwent adenotonsillectomy had a greater decrease in UMPSQ scores than those who did not (P=0.03). Patients with significant LPW collapse were more likely to have adenotonsillectomy (P=0.001), while patients with higher Yellon tongue base scores were less likely (P=0.005). There was no statistically significant relationship between OSA severity and whether adenotonsillectomy was performed.
conclusionsDISE is a valuable tool for evaluating children with multi-level obstruction, and findings change surgical decision-making for children without enlarged tonsils. Adenotonsillectomy resulted in the greatest decrease in OSA symptoms, but was mainly performed on patients with significant LPW collapse.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.