Evidence map›Paper›PMID 40519213›Full record

Articlenpj women's health2025

Untargeted metabolomics reveals key pathways in miscarriage: steroid, folate, fatty acid & glycosaminoglycan metabolism.

Chee Wai Ku, Yu Bin Tan, Kuan Yang Chew, Chee Onn Ku, Shi Tong Carissa Ng, Thiam Chye Tan, Yie Hou Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in npj women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chee Wai Ku *Department of Reproductive Medicine, KK Women's and Children's Hospital, Singapore, Singapore.
Yu Bin Tan *Duke-NUS Medical School, Singapore, Singapore.
Kuan Yang ChewLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Chee Onn KuFaculty of Science, National University of Singapore, Singapore, Singapore.
Shi Tong Carissa NgYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Thiam Chye TanOBGYN-Academic Clinical Program, Duke-NUS Medical School, Singapore, Singapore.
Yie Hou LeeOBGYN-Academic Clinical Program, Duke-NUS Medical School, Singapore, Singapore.ORCID 0000-0003-2723-2023

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolites influencing miscarriage outcomes remain understudied. We hypothesized that aberrant metabolism impacts threatened miscarriage outcomes and that understanding these pathways could offer new management strategies. This case-control study analyzed serum metabolomics from 80 women between 5 and 12 weeks' gestation at KK Women's and Children's Hospital, Singapore, comparing three groups: women with threatened miscarriage who miscarried (TM

Indexed as

Reproductive biologyReproductive disorders

Identifiers

PMID40519213
PMCPMC12165837

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.