Evidence map›Paper›PMID 40518931›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025

Use of a novel, non-continuous aspiration pump during mechanical thrombectomy: An in vitro study.

K Rose Duncan, Dana Defta, Brian Jankowitz, Yin C Hu

Abstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

K Rose DuncanDepartment of Neurological Surgery, Case Western Reserve University, University Hospitals, Cleveland, OH, USA.ORCID 0000-0001-8475-8246
Dana DeftaDepartment of Neurological Surgery, Case Western Reserve University, University Hospitals, Cleveland, OH, USA.
Brian JankowitzDepartment of Neurological Surgery, John F. Kennedy University, JFK University Medical Center, Pleasant Hill, CA, USA.ORCID 0000-0001-9306-0763
Yin C HuDepartment of Neurological Surgery, Case Western Reserve University, University Hospitals, Cleveland, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundAspiration thrombectomy has become a standard tool for clot extraction in ischemic stroke. The ALGO Smart Pump (Von Vascular, Sunrise, FL) utilizes novel non-continuous aspiration and real-time objective data with the intent of increasing clot ingestion and first-pass effect while reducing distal emboli and time to reperfusion.MethodsFive different catheters were used to test clot extraction with the ALGO pump in a Mentice flow model. Clot extraction time, clot length, clot lodging or "corking" within the catheter, first-pass effect, distal embolization, and catheter distortion were assessed for each thrombectomy procedure. Thirty thrombectomies were performed with each catheter for a total of 150 thrombectomies.ResultsAll trials achieved reperfusion on the first pass. Complete clot ingestion with resumption of free flow through the catheter was seen in 65.3% of trials, with the remainder involving corking of the clot in the catheter or at the catheter tip. When the clot became corked, 63.3% of the time it was corked completely within the catheter; in the other 36.7%, the clot was corked at the catheter tip. Distal emboli were seen in 3.3% of trials. No evidence of catheter distortion was observed.Discussion/ConclusionThe ALGO non-continuous aspiration pump is effective at clot extraction with a wide range of catheters in the in vitro model. The low incidence of catheter tip-corking and distal emboli as well as the high first-pass reperfusion rate suggests the possibility of improved reperfusion with non-continuous aspiration.

Indexed as

Aspiration pumpendovascular thrombectomymechanical thrombectomystroke

Identifiers

PMID40518931
PMCPMC12170549

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.