Evidence map›Paper›PMID 40518838›Full record

ReviewThe Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association2026

The Psychosocial Impact of Cleft Lip and/or Palate on Caregivers and Individuals in Low- and Middle-Income Countries: A Narrative Review.

Nicola M Stock, Bruna Costa, Anna Zarola, Allyn Auslander, Hugh Brewster, Phyllida Swift, Leela Imam, Usama Hamdan, Gareth Davies, Sara Horne and 1 more

Abstract readReview
In one paragraph

Review in The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Positive Longitudinal Caregiver Behavioral Ratings and Self-Reported Quality of Life in Youth With Cleft Lip and Palate in Treatment for Class III Malocclusion.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nicola M StockCentre for Appearance Research, University of the West of England, Bristol, UK.ORCID 0000-0002-1285-691X
Bruna CostaCentre for Appearance Research, University of the West of England, Bristol, UK.
Anna ZarolaCentre for Appearance Research, University of the West of England, Bristol, UK.
Allyn AuslanderOperation Smile, Virginia Beach, Virginia, USA.
Hugh BrewsterTransforming Faces, Toronto, Ontario, Canada.
Phyllida SwiftFace Equality International, London, UK.
Leela ImamSmile Train, Bengaluru, India.
Usama HamdanGlobal Smile Foundation, Westwood, MA, USA.ORCID 0000-0003-3654-7262
Gareth DaviesEuropean Cleft Organisation, Perpignan, France.
Sara HorneDirector of Global Speech and Hearing Programs, Smile Train, Fort Lauderdale, FL, USA.
Priti P DesaiOperation Smile, Virginia Beach, Virginia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low- and middle-income countries (LMICs) represent the highest incidence, morbidity, and Disability Adjusted Life Years for cleft lip and/or palate (CL/P) globally. Most cleft care models now include psychosocial support, yet the psychosocial impacts of CL/P in LMICs are understudied. This narrative review aimed to synthesize published literature to provide a foundation for future research and evidence-based psychosocial support. Seventy-one peer-reviewed articles published between September 2003 and July 2024 were included. Themes pertaining to caregivers included Social Experiences, Emotional Well-Being, Treatment Experiences, and overall Quality of Life. Themes regarding individuals with CL/P included Developmental Trajectory, Social Integration, Emotional Health, Satisfaction with Treatment, and Health-Related Quality of Life. Most articles focused on upper-middle-income countries. East Asia and Pacific was the most studied geographical region in LMICs, while Europe and Central Asia was the least studied. Only 28 of 135 LMICs (20.7%) were represented in the included psychosocial literature. Most studies (69%) utilized a quantitative design. Sample sizes ranged from 2 to 295, with 73% of studies recruiting from a single site. Few studies (28%) compared their data to reference or control groups. Just over half of studies used standardized, validated measures. Most studies were led by LMIC teams. This review calls for ongoing monitoring of psychological health in individuals with CL/P and their caregivers and coordinated investment into multifaceted psychosocial program in LMICs. Building practice-relevant research capacity in LMICs to develop the evidence-base is essential.

Indexed as

CaregiversCleft LipCleft PalateDeveloping CountriesHumansQuality of LifeSocial Supportcleft lip and palateLMIClow-incomemiddle-incomepsychosocial adjustmentquality of life

Identifiers

PMID40518838
PMCPMC13176505

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.