ArticleJournal of the Chinese Medical Association : JCMA2025
Outcomes of endovascular thrombectomy in acute ischemic stroke patients air-transferred from Kinmen to mainland Taiwan.
Article in Journal of the Chinese Medical Association : JCMA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundSince 2018, Taipei Veterans General Hospital (TPEVGH) has performed endovascular thrombectomy (EVT) on acute ischemic stroke patients air-transferred from Kinmen Hospital (KMH). This study evaluated the clinical profiles and outcomes of these patients, comparing them to those treated directly at TPEVGH.
methodsIn this retrospective study, we included consecutive acute ischemic stroke patients air-transferred from KMH to TVGH for EVT between January 2018 and April 2024. A comparison group comprised patients who presented directly to TVGH and underwent EVT during the same period. Transfer decisions at KMH were based on clinical presentation and neuroimaging evidence of large vessel occlusion. Only patients with salvageable brain tissue (substantial penumbra without a large infarct core) were transferred. Exclusion criteria included a premorbid modified Rankin Scale (mRS) score ≥3, in-hospital stroke, serious advanced illness, or life expectancy <6 months. Primary outcomes were 90-day functional independence (mRS 0-2), 30-day mortality, and symptomatic intracranial hemorrhage (sICH). Analyses included Mann-Whitney, χ 2 tests, and multivariate logistic regression.
resultsA total of 275 patients were included: 15 from KMH (mean age 71.1 ± 11.7 years; 40% male; median National Institutes of Health Stroke Scale [NIHSS] 15) and 260 from TVGH (mean age 73.5 ± 13.6 years; 53% male; median NIHSS 18). KMH patients had longer onset-to-door times (median [interquartile range {IQR}] = 452.0 [400.0] vs 217.0 [442.8] minutes; p < 0.001] but shorter door-to-puncture times (121.5 [43.5] vs 144.0 [55.3] minutes; p = 0.031). Among KMH patients, the substantial reperfusion rate was 73.3%, 90-day functional independence was 40.0%, sICH rate was 13.3%, and 30-day mortality was 13.3%, outcomes comparable to those of TPEVGH patients.
conclusionDespite longer transfer times, air-transferred patients achieved similar safety and efficacy outcomes after EVT compared with directly treated patients. Further studies are warranted to optimize transfer strategies and patient selection.
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