Evidence map›Paper›PMID 40518591›Full record

ArticlePaediatric and perinatal epidemiology2026

Time-Varying Associations Between Physical Activity and Injury Risk Among Children.

Chinchin Wang, Michal Abrahamowicz, Marie-Eve Beauchamp, Jay S Kaufman, Russell J Steele, Eva Jespersen, Niels Wedderkopp, Ian Shrier

Abstract read
In one paragraph

Article in Paediatric and perinatal epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chinchin WangDepartment of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada.ORCID https://orcid.org/0000-0002-8472-9936
Michal AbrahamowiczDepartment of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada.ORCID https://orcid.org/0000-0002-3172-3952
Marie-Eve BeauchampCentre for Outcomes Research and Evaluation, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.ORCID https://orcid.org/0000-0001-9488-0157
Jay S KaufmanDepartment of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada.ORCID https://orcid.org/0000-0003-1606-401X
Russell J SteeleDepartment of Mathematics and Statistics, McGill University, Montreal, Quebec, Canada.ORCID https://orcid.org/0000-0003-1071-0914
Eva JespersenDepartment of Oncology, Odense University Hospital, Odense, Denmark.ORCID https://orcid.org/0000-0002-8942-4816
Niels WedderkoppDepartment of Clinical Research, University of Southern Denmark, Odense, Denmark.ORCID https://orcid.org/0000-0002-9660-6618
Ian ShrierCentre for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada.ORCID https://orcid.org/0000-0001-9914-3498

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhysical activity has time-varying associations with injury risk among children. While previous activity may predispose to injury through tissue damage, fatigue and insufficient recovery, it may protect against injury by strengthening tissues and improving fitness and skills. It is unclear what the relevant time window and relative importance of past activity are with regard to current injury risk in children.

objectivesThe objectives of this study were to assess how previous activity patterns are associated with injury risk among children.

methodsOur data source was the Childhood Health, Activity, and Motor Performance School Study Denmark (CHAMPS-DK), a prospective cohort study of Danish school children conducted between 2008 and 2014. We applied flexible weighted cumulative exposure methods within a Cox proportional hazards model to estimate the time-varying association between the number of weekly activity sessions and time-to-first injury in each school year. We estimated several models with varying time windows and compared goodness-of-fit.

resultsOut of 1667 study participants, 986 (59.1%) were injured at least once, with a total of 1752 first injuries across school years. The best-fitting model included 20 weeks of past physical activity. Higher levels of activity performed 10-20 weeks ago were associated with decreased injury risk, while higher levels of activity performed 2-9 weeks ago were associated with higher injury risks. Compared to those who remained minimally active for the entire past 20-week period, children who were highly active in the past 10 weeks after being minimally active 11-20 weeks ago had an injury hazard ratio of 1.63 (95% confidence interval 1.18, 2.23).

conclusionsFlexible weighted cumulative exposure methods suggest a complex temporal relationship between past physical activity history and injury in children.

Indexed as

ExerciseWounds and InjuriesChildDenmarkFemaleHumansMaleProportional Hazards ModelsProspective StudiesRisk FactorsTime Factorsadolescentchildexercisefatigueweighted cumulative exposurewounds and injuries

Identifiers

PMID40518591
PMCPMC13010222

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.