Trial reportInfant mental health journal2025
An intervention to address prenatal anxiety improves maternal-infant bonding, with effects mediated by maternal-infant responsiveness, maternal self-efficacy, and postpartum depression.
Trial report in Infant mental health journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- A psychosocial intervention for prenatal anxiety decreases functional disability among pregnant Pakistani women: A moderated mediation approach using data from a randomized controlled trial.Journal of psychosomatic research · 2025Trial
- The relationship between maternal attachment, maternal self-efficacy, and postpartum depressive symptoms in mothers during the early postpartum period: a cross-sectional study.BMC pregnancy and childbirth · 2026Article
- Receipt of a psychosocial intervention for prenatal anxiety and risk of perinatal intimate partner violence in Pakistani women.PLOS global public health · 2025Article
Corrections and comments
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Authors and funding
7 authors.
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Abstract
Prenatal anxiety is associated with poor postpartum infant-child relationships. Thus strategies that improve prenatal anxiety could also affect this relationship. We investigated the effects of an intervention to address prenatal anxiety on maternal-infant bonding and examined the potential mediating roles of maternal self-efficacy, maternal-infant responsiveness, and postpartum depression. Data were collected between 2019 and 2022 as part of a randomized controlled trial to treat prenatal anxiety using cognitive behavioral therapy. Participants included 701 pregnant women aged 18 or older with symptoms of anxiety, but not depression, attending a tertiary hospital in Rawalpindi, Pakistan. Women randomized to the intervention arm demonstrated significantly lower scores on the postpartum bonding questionnaire (B = -3.05, 95% CI: -4.98, -1.12), indicating stronger bonding. Responsiveness, self-efficacy, and postpartum depression significantly mediated 38%, 66%, and 95% of the association between the intervention and bonding, respectively. These mediators may be useful targets to improve maternal-infant bonding among women with prenatal anxiety.
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Registered trials
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