ArticleJournal of orthopaedic surgery and research2025
Predictive value of Hounsfield units and vertebral bone quality on cage subsidence in oblique lateral interbody fusion with bilateral posterior fixation.
Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- C-VBQ and CT hounsfield units for DXA-defined low bone mass screening and their associations with bone turnover markers.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- C- VBQ versus CT Hounsfield units in predicting cage subsidence following ACDF: a retrospective cohort analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Preoperative imaging predictors of subsidence of 3D-printed artificial cervical vertebral bodies: a cohort study of 102 patients with nomogram development and validation.BMC musculoskeletal disorders · 2026Article
- Retrospective Analysis of Imaging Influencing Factors and Early Stability of Cage Subsidence After Percutaneous Endoscopic Lumbar Interbody Fusion.Journal of pain research · 2026Article
- Opportunistic screening of osteoporosis in lung transplant recipients: diagnostic value of pre-transplant thoracic CT using vertebral Hounsfield units.Journal of orthopaedic surgery and research · 2025Article
- From complexity to clarity: A perspective on personalized spine care through genetic, psychosocial, and technological advancements.Journal of craniovertebral junction & spineReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
backgroundCage subsidence (CS) is a significant complication following oblique lateral interbody fusion combined with bilateral pedicle screw fixation (OLIF-BPSF) in patients with spinal degenerative diseases (SDDs). Identifying reliable predictors of CS is crucial for optimizing surgical outcomes.
methodsThis retrospective cohort study included 314 SDD patients who underwent OLIF-BPSF between July 2019 and July 2023. Preoperative Hounsfield unit (HU) values and vertebral bone quality (VBQ) scores were measured. Statistical analyses included correlation matrices, Kaplan-Meier survival analysis, Cox proportional hazards models, restricted cubic splines, and receiver operating characteristic (ROC) curve analysis. Sensitivity analyses were performed to ensure robustness.
resultsCS occurred in 13.38% of patients. Lower global (HR: 0.97, 95% CI: 0.97-0.99) and segmental (HR: 0.97, 95% CI: 0.95-0.98) HU values were significantly associated with higher CS incidence, whereas higher global (HR: 1.67, 95% CI: 1.29-2.16) and segmental (HR: 1.68, 95% CI: 1.30-2.17) VBQ scores were also significantly associated with increased CS risk. A nonlinear relationship was observed between the VBQ score and CS, with CS incidence significantly increasing when the global VBQ score was ≥ 2.67 or the segmental VBQ score was ≥ 2.49. ROC analysis demonstrated good predictive performance for HU values and VBQ scores, with segmental HU values showing superior incremental predictive value (AUC: 0.82). The findings remained consistent across various sensitivity analyses.
conclusionHU values and VBQ scores independently predict CS in SDD patients undergoing OLIF-BPSF. Incorporating these metrics into preoperative assessments may enhance risk stratification and guide personalized surgical planning.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.