SynthesisNeurosurgical review2025
The effectiveness of clinical frailty assessment in older patients with Traumatic brain injury in predicting outcome and quality of life: a systematic review.
Synthesis in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Management and outcome of patients with traumatic brain injury treated in three major Nordic intensive care units: a comparative cohort study.Scandinavian journal of trauma, resuscitation and emergency medicine · 2026Observational
- CT-positive traumatic brain injury in patients ≥ 80 years: mortality and 6-months functional outcome.Acta neurochirurgica · 2026Article
- Traumatic brain injury among older adults: urgent need for implementation of specific rehabilitation needs and tailored to low-middle-context.Frontiers in human neuroscience · 2026Article
- Consensus on the management of traumatic brain injury in older adults: Results from a Delphi study.Brain & spine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ground-level falls are the most common cause of Traumatic brain injury (TBI) leading to emergency hospital admissions, in adults aged 65 years and older. The world's population is ageing and frailty is becoming more relevant in healthcare provision, therefore assessment of frailty on admission is integral to care planning. Identifying whether frailty is a risk factor for poor outcomes may facilitate clinical decision making and direct care appropriately. This review aimed to evaluate the effectiveness of a clinical frailty assessment or scale in predicting outcomes in older patients following a TBI, including mortality, functional recovery, hospital length of stay, and discharge disposition. A systematic review of OVID, EBSCO, Elsevier and Wiley from 2005 to 2025. Included a majority of patients aged 65 years and over, diagnosed with a TBI with a validated frailty assessment tool and at least one outcome measure reported. A total of 12 observational studies (464,606 patients) were included, with a mean age ranging between 70 and 83 years. These studies utilised seven distinct frailty assessment tools. Falls from standing were the most common mechanism of injury identified. Frailty was associated with 30-day and 1-year mortality and unfavourable outcome in combination with a reduced Glasgow Coma Score (GCS) on admission. Frailty was an independent predictor of length of hospital stay, discharge disposition and functional recovery but no study used a validated quality of life tool. Various frailty assessment tools demonstrate effectiveness in predicting clinical outcomes when used in combination with patients age, co-morbidity and neurological evaluation. The predictive value of these tools supports their clinical utility in clinical decision making. Further prospective research is needed to understand how frailty relates to longer term outcomes, particularly quality of life, which was not measured in the included studies. Clinical trial number Not applicable.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.