Evidence map›Paper›PMID 40518495›Full record

Trial reportAIDS and behavior2025

Health-Related Quality of Life Among People Living with HIV in Vietnam, a Three-Year Longitudinal Analysis.

Hao T Duong, Cuong D Do, Donn J Colby, Todd M Pollack

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in AIDS and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hao T DuongDepartment of Medicine, Baylor College of Medicine, 2450 Holcombe Blvd (Office), Houston, TX, 77021, USA. hao.duong@bcm.edu.ORCID http://orcid.org/0009-0007-2086-7209
Cuong D DoCenter for Tropical Diseases, Bach Mai Hospital, Hanoi, Vietnam.
Donn J ColbyCenter for Applied Research on Men and Community Health, Ho Chi Minh City, Vietnam.
Todd M PollackDepartment of Medicine, Beth Israel Deaconess Medical Center, Boston, USA.

Funding

Roche Diagnostics 974
6 · The paper itself

Abstract

This study examined changes in health-related quality of life (HRQOL) among people living with HIV in Vietnam over three years following antiretroviral therapy (ART) initiation. We analyzed data from a randomized trial of 639 ART-naïve patients in which HRQOL was measured using the SF-8 instrument. Mixed effects logistic regression was used to assess changes in HRQOL over time and identify associated factors. At baseline, 57.5% reported low HRQOL. HRQOL improved rapidly after ART initiation, with 89.0% reporting good HRQOL at 3 months and 96.4% at 36 months. Compared with men, women had slower improvement in HRQOL over time. Factors positively associated with HRQOL included higher BMI and alcohol use, while food insecurity, history of tuberculosis, advanced clinical stages, and TDF-based regimens were negatively associated. Older age was linked to poorer HRQOL outcomes. These findings highlight the effectiveness of ART in improving HRQOL while also revealing disparities in HRQOL improvements.

Indexed as

Anti-HIV AgentsHealth StatusHIV InfectionsQuality of LifeAdultFemaleHumansLogistic ModelsLongitudinal StudiesMaleMiddle AgedSocioeconomic FactorsSurveys and QuestionnairesVietnamAnti-HIV AgentsARTHIVHRQOLLongitudinal studyPLHIVQuality of lifeSF-8Vietnam

Identifiers

PMID40518495

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.