Evidence map›Paper›PMID 40518494›Full record

Trial reportAIDS and behavior2025

Social Determinants of Mental Health Outcomes Among Refugee Adolescents and Youth Living with HIV in Refugee Settlements in Uganda: A Cross-Sectional Analysis.

Nhial T Tutlam, Samuel Kizito, Proscovia Nabunya, Mitra Naseh, Imelda Nabbosa, Isaac Kwesiga, Phionah Namatovu, Ozge Sensoy Bahar, Noeline Nakasujja, Fred M Ssewamala

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in AIDS and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01790373 (Suubi+Adherence), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01790373 naactive not recruitingnot on this map

Suubi+Adherence: Evaluating a Youth-Focused Economic Empowerment Approach to HIV Treatment Adherence

TypeinterventionalSponsorWashington University School of MedicineRan2013 to 2026Enrolled702ConditionsHIVArmsSuubi+Adherence, Bolstered Standard of Care
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nhial T TutlamInternational Center for Child Health and Development, Brown School of Social Work, Washington University in St. Louis, One Brookings Drive, St. Louis, MO, 63130, USA. ntutlam@wustl.edu.ORCID http://orcid.org/0000-0001-9365-1539
Samuel KizitoInternational Center for Child Health and Development, Brown School of Social Work, Washington University in St. Louis, One Brookings Drive, St. Louis, MO, 63130, USA.ORCID http://orcid.org/0000-0003-2413-0398
Proscovia NabunyaInternational Center for Child Health and Development, Brown School of Social Work, Washington University in St. Louis, One Brookings Drive, St. Louis, MO, 63130, USA.ORCID http://orcid.org/0000-0002-9088-5839
Mitra NasehInternational Center for Child Health and Development, Brown School of Social Work, Washington University in St. Louis, One Brookings Drive, St. Louis, MO, 63130, USA.ORCID http://orcid.org/0000-0002-1717-3173
Imelda NabbosaInternational Center for Child Health and Development Field Office, Plot 23 Circular Rd, Masaka, Uganda.
Isaac KwesigaInternational Center for Child Health and Development Field Office, Plot 23 Circular Rd, Masaka, Uganda.
Phionah NamatovuInternational Center for Child Health and Development Field Office, Plot 23 Circular Rd, Masaka, Uganda.ORCID http://orcid.org/0000-0001-6197-4413
Ozge Sensoy BaharInternational Center for Child Health and Development, Brown School of Social Work, Washington University in St. Louis, One Brookings Drive, St. Louis, MO, 63130, USA.ORCID http://orcid.org/0000-0002-7230-0438
Noeline NakasujjaDepartment of Psychiatry, School of Medicine, College of Health Sciences, Makerere University, P. O. Box 7072, Kampala, Uganda.ORCID http://orcid.org/0000-0002-8163-4376
Fred M SsewamalaInternational Center for Child Health and Development, Brown School of Social Work, Washington University in St. Louis, One Brookings Drive, St. Louis, MO, 63130, USA.ORCID http://orcid.org/0000-0002-4849-5650

Funding

Suubi+Adherence-R2: Examining the longitudinal HIV treatment adherence among youth living with HIV (YLHIV) transitioning into young adulthoodR01HD074949 · NICHD · WASHINGTON UNIVERSITY · PI NABUNYA, PROSCOVIA, SENSOY BAHAR, OZGE · 2012 to 2024
$7.7M
Eunice Kennedy Shriver National Institute of Child Health and Human Development R01HD074949-09S1Global Health Center at Washington University in St. Louis Global Health Center at Washington University in St. LouisMcDonnell International Scholars Academy, Washington University in St. Louis McDonnell International Scholars Academy, Washington University in St. LouisNICHD NIH HHS R01 HD074949
6 · The paper itself

Abstract

Although the prevalence of mental disorders is high among conflict-affected populations, the extent to which social determinants impact the mental health of conflict-affected youth living with HIV is not well studied. The goal of this study was to investigate how social determinants impact the mental health of refugee adolescents and youth living with HIV in Uganda (RAYLHIV). We analyzed baseline data from a two-year cluster randomized clinical trial (RCT) among RAYLHIV (ages 13-30). The participants were recruited between July and December 2023 from 20 health centers in three refugee settlements. To examine the association between selected social determinants of mental health (SDoMH) and the mental health outcomes, we fitted a separate mixed-effects linear regression model for each outcome including depression, hopelessness, and PTSD. HIV-related stigma (β = 0.04, 0.01-0.07; p = 0.012) and PTSD (β = 0.29, 0.16-0.43; p = < 0.001) were associated with increased depressive symptoms. Similarly, unemployment (β = 2.39, 0.65-4.13; p 0.007), HIV-related stigma (β = 0.20, 0.09-0.31; 0.001) and PTSD (β = 1.55, 0.84-2.26; p < 0.001) were associated with hopelessness. Good physical health (β = -0.53, -1.00-0.06; p = 0.028) and school enrollment (β = -0.94, -1.3-0.50; p < 0.001) were associated with lower PTSD symptoms. This study found that social determinants including school enrollment, double orphanhood, HIV-related stigma, poor physical health, and poverty related factors like unemployment are important predictors of poor mental health among RAYLHIV, underscoring the need for multilevel approaches to address these challenges.Trial registration: NCT01790373.

Indexed as

DepressionHIV InfectionsMental HealthRefugeesSocial Determinants of HealthStress Disorders, Post-TraumaticAdolescentAdultCross-Sectional StudiesFemaleHumansMaleSocial StigmaUgandaYoung AdultRefugee adolescents and youthRefugee settlementsRefugee youth living with HIVSocial determinants of mental health

Identifiers

PMID40518494
PMCPMC12933638

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.