SynthesisClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2025
Yield of Advanced Neoplasia at Second Post-polypectomy Surveillance Colonoscopy: A Systematic Review and Meta-analysis.
Synthesis in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05994482 (Surveillance Colonoscopy in Older Adults), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Surveillance Colonoscopy in Older Adults: The SurvOlderAdults Study
Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
BACKGROUND &
aimsIndividuals who have had polypectomy and at least one surveillance colonoscopy exam are routinely encountered, but evidence to inform risk for subsequent neoplasia and timing of surveillance is limited. Our aim was to conduct a systematic review and meta-analysis of serial surveillance yield.
methodsWe performed a systematic search of research literature databases through September 2024 and identified studies reporting neoplasia yield at baseline colonoscopy and at least 2 surveillance colonoscopies. Summary estimates of advanced neoplasia rates at second surveillance, according to baseline and first surveillance finding combinations (no adenoma, nonadvanced neoplasia, or advanced neoplasia) were pooled.
resultsThe pooled analysis included 5912 individuals from 11 observational studies. The proportion with advanced neoplasia at second surveillance among those with baseline no adenoma was 4% (95% confidence interval [CI], 2.5%-6.5%) after no adenoma, 7.2% (95% CI, 5.5%-9.4%) after nonadvanced neoplasia, and 11.4% (95% CI, 7.4%-17.2%) after advanced neoplasia at first surveillance, respectively. The proportion with advanced neoplasia at second surveillance among those with baseline nonadvanced neoplasia was 5.4% (95% CI, 3.7%-7.9%) after no adenoma, 9.1% (95% CI, 6.7%-12.3%) after nonadvanced neoplasia, and 20.2% (95% CI, 15.4%-25.9%) after advanced neoplasia at first surveillance, respectively. The proportion with advanced neoplasia at second surveillance among those with baseline advanced neoplasia was 9.1% (95% CI, 6.2%-13.0%) after no adenoma, 12.8% (95% CI, 9.5%-17.0%) after nonadvanced neoplasia, and 26.1% (95% CI, 18.4%-35.5%) after advanced neoplasia at first surveillance, respectively.
conclusionsThese findings support the concept of using results from both the baseline and first surveillance colonoscopies to provide a more accurate risk estimate than using results of only the most recent colonoscopy.
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