ArticleAmerican journal of preventive medicine2025
Medical Cannabis and Psychological Well-Being in Illinois' Opioid Alternative Pilot Program.
Article in American journal of preventive medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionIn Illinois, the Opioid Alternative Pilot Program was implemented to provide individuals access to medical cannabis as a direct substitute for opioids. Despite medical cannabis being frequently used for mental health symptoms, little is known about medical cannabis' role on overall psychological well-being. Hence, the objective of this study is to examine the association of medical cannabis use with psychological well-being among the first Opioid Alternative Pilot Program cohort.
methodsA survey was sent from February-July 2019 to those who enrolled in the Opioid Alternative Pilot Program. Cannabis users (n=626) were compared with nonusers (n=234) to determine whether there was an association between cannabis use within the past year and psychological well-being. Psychological well-being was measured on a scale of 1-5 (1 being poor and 5 being excellent). Backward stepwise regression models were used. Sensitivity analysis was also conducted to determine whether there was an association between regular cannabis use (using 3 or more times a week) and no cannabis use.
resultsThe study sample included 860 participants. The average age was 47 (SD=14.2) years; 60% of the cohort was male; 72% were not of Hispanic, Latino, or Spanish origin; 67% were married; and 67% of cannabis users reported having a disability. The average perceived psychological well-being was 3.18 (SD=0.94) (good), with no statistically significant difference in psychological well-being between the 2 groups (users: 3.21 [SD=1.01]; nonusers: 3.12 [SD=0.71]; p=0.18).
conclusionsIn this cohort of Opioid Alternative Pilot Program participants, there was no clinically meaningful difference in psychological well-being between cannabis users and nonusers.
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