Evidence map›Paper›PMID 40517421›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2026

Long-term clinical and MRI outcomes of a polyurethane meniscal scaffold implantation for the treatment of partial meniscal deficiency: A minimum 10-year follow-up study.

Vasileios S Akrivos, George A Komnos, Bela Ujvari, Artemis Hante, Eleftheria Adaktylidou, Theofilos Karachalios, Michael Hantes

Abstract read
In one paragraph

Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vasileios S AkrivosDepartment of Orthopaedic Surgery and Musculoskeletal Trauma, Faculty of Medicine, School of Health Sciences, University of Thessalia, Larissa, Greece.ORCID https://orcid.org/0009-0008-7889-3829
George A KomnosDepartment of Orthopaedic Surgery and Musculoskeletal Trauma, Faculty of Medicine, School of Health Sciences, University of Thessalia, Larissa, Greece.ORCID https://orcid.org/0000-0002-6832-0014
Bela UjvariDepartment of Traumatology, University of Semmelweiss, Budapest, Hungary.
Artemis HanteDepartment of Physiotherapy, International Hellenic University, Nea Moudania, Greece.
Eleftheria AdaktylidouDepartment of Orthopaedic Surgery and Musculoskeletal Trauma, Faculty of Medicine, School of Health Sciences, University of Thessalia, Larissa, Greece.
Theofilos KarachaliosDepartment of Orthopaedic Surgery and Musculoskeletal Trauma, Faculty of Medicine, School of Health Sciences, University of Thessalia, Larissa, Greece.ORCID https://orcid.org/0000-0002-9043-0535
Michael HantesDepartment of Orthopaedic Surgery and Musculoskeletal Trauma, Faculty of Medicine, School of Health Sciences, University of Thessalia, Larissa, Greece.ORCID https://orcid.org/0000-0001-9494-6048

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the clinical and magnetic resonance imaging (MRI) results after implantation of a polyurethane scaffold for chronic segmental meniscus deficiency following partial meniscectomy in a long-term follow-up. STUDY

designLevel IV, retrospective case series.

methodsThirty-two knees received arthroscopic implantation of an Actifit® polyurethane meniscal implant for deficiency of the meniscus. Clinical outcomes were assessed using patient-reported outcome scores, including Knee injury and Osteoarthritis Outcome Score (KOOS), Lysholm, Tegner Activity Scale and visual analogue scale (VAS) for pain and satisfaction. Preoperative MRI scans and final follow-up radiographs and MRI evaluations were performed to assess scaffold morphology, tissue integration and the status of the articular cartilage.

resultsThe mean follow-up was 11.4 years. Significant improvements were observed in clinical outcomes, with KOOS improving from a preoperative mean of 47.75 (standard deviation [SD]: 16.88) to a 78.62 (SD: 15.45), Lysholm scores from 46.62 (SD: 16.96) to 84.62 (SD: 13.03), Tegner Activity Scale improving from 1.8 to 4.1 at the final follow-up. The VAS for pain decreased from a preoperative mean of 5.62 (SD: 2.54) to 2.12 (SD: 2.02). MRI evaluations using the Genovese classification showed 23 knees with Type II scaffolds, 0 with Type III and 9 with Type I. Bone oedema was not present in 27 knees, with 5 knees showing Type I bone oedema. Meniscal extrusion was observed in 24 knees with partial extrusion and 8 knees with complete extrusion. The contralateral meniscus was normal in 28 knees and graded as Reicher Grade 1 in 2 knees. The Kellgren-Lawrence classification revealed 15 knees with Type I osteoarthritic changes, 10 with Type II changes and 7 with Type III changes.

conclusionArthroscopic treatment for patients with chronic segmental meniscal loss using a polyurethane meniscal implant can achieve sustainable long-term results regarding pain reduction and knee function. However, the MRI did not reveal normal menisci in all cases. LEVEL OF EVIDENCE: Level IV.

Indexed as

MeniscectomyMenisci, TibialTibial Meniscus InjuriesTissue ScaffoldsAdultArthroscopyFemaleFollow-Up StudiesHumansMagnetic Resonance ImagingMaleMiddle AgedPatient Reported Outcome MeasuresPolyurethanesRetrospective StudiesTreatment OutcomePolyurethanesActifitirreparable meniscal defectmeniscuspartial meniscectomypolyurethane scaffoldscaffold

Identifiers

PMID40517421
PMCPMC13122752

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.