Evidence map›Paper›PMID 40517134›Full record

ArticleJournal of investigative medicine high impact case reports

Beyond The Usual Suspects: Primary Breast Lymphoma Incidentally Detected With Routine Mammographic Screening.

Thomas Wright, Jowan Al-Nusair, Reesha Bodiwala, Samhitha Gundakaram, Swapna Sirigireddy, Zakaria Alagha, Saadia Haleema, Mahmoud Abdallah, Muhammad Omer Jamil

Abstract readCase Reports
In one paragraph

Article in Journal of investigative medicine high impact case reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thomas WrightMarshall University Joan C Edwards School of Medicine Department of Internal Medicine, Huntington, WV, USA.ORCID 0009-0007-6324-7464
Jowan Al-NusairMarshall University Joan C Edwards School of Medicine Department of Internal Medicine, Huntington, WV, USA.ORCID 0000-0002-7183-5940
Reesha BodiwalaMarshall University Joan C Edwards School of Medicine Department of Internal Medicine, Huntington, WV, USA.ORCID 0009-0004-0270-173X
Samhitha GundakaramMarshall University Joan C Edwards School of Medicine Department of Internal Medicine, Huntington, WV, USA.
Swapna SirigireddyMarshall University Joan C Edwards School of Medicine Department of Internal Medicine, Huntington, WV, USA.
Zakaria AlaghaMarshall University Joan C Edwards School of Medicine Department of Internal Medicine, Huntington, WV, USA.
Saadia HaleemaMarshall University Joan C Edwards School of Medicine Department of Pathology, Huntington, WV, USA.
Mahmoud AbdallahMarshall University Joan C Edwards School of Medicine Department of Hematology and Oncology, Huntington, WV, USA.
Muhammad Omer JamilMarshall University Joan C Edwards School of Medicine Department of Hematology and Oncology, Huntington, WV, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary breast lymphoma (PBL) is a rare type of non-Hodgkin's lymphoma, comprising less than 1% of all lymphomas and 0.5% of breast malignancies. The majority of PBL cases are of B-cell origin, with diffuse large B-cell lymphoma (DLBCL) being the most common subtype, though follicular lymphoma (FL) also occurs. We present a case of a 74-year-old woman whose routine mammogram revealed a 1.5 cm mass in the right breast. Ultrasound and biopsy confirmed the presence of classic follicular lymphoma, with B-cell markers CD20, CD10, Bcl-6, and Bcl-2. A PET scan and biopsy of the left periaortic lymph node identified additional disease, confirming stage III FL. The patient was asymptomatic and exhibited favorable prognostic factors, including normal beta-2 microglobulin and LDH levels. Due to the indolent nature of her disease and low tumor burden, the decision was made to pursue active surveillance rather than immediate treatment. This case highlights the diagnostic challenges of PBL and the importance of personalized management, particularly in asymptomatic patients with low disease burden.

Indexed as

Breast NeoplasmsLymphoma, FollicularLymphoma, Large B-Cell, DiffuseAgedBiopsyFemaleHumansIncidental FindingsMammographyPositron-Emission Tomographybreast neoplasms and hematologic malignanciesfollicular lymphomanon-Hodgkin’s lymphoma (NHL)primary breast lymphoma

Identifiers

PMID40517134
PMCPMC12171245

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.