Evidence map›Paper›PMID 40515899›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

Analysis of the Virus-Host Protein-Protein Interaction via Co-Immunoprecipitation (Co-IP).

Hongjuan You, Chunfu Zheng

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hongjuan YouDepartment of Pathogenic Biology and Immunology, Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Chunfu ZhengDepartment of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, AB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Virus-host interactions play crucial roles throughout the entire process of viral replication. Specific viral proteins often target key proteins of the host. These interactions can be identified through various experimental techniques. Co-immunoprecipitation (co-IP) is a powerful method for detecting and characterizing protein-protein interactions and understanding their functional significance. In this context, Co-IP is commonly used to screen and identify viral proteins that interact with host proteins, providing valuable insights into the mechanisms of viral replication.

Indexed as

Host-Pathogen InteractionsImmunoprecipitationProtein Interaction MappingViral ProteinsHumansProtein BindingVirus ReplicationViral ProteinsProtein interactionViral proteinVirus

Identifiers

PMID40515899

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.