Evidence map›Paper›PMID 40515817›Full record

ArticlePediatric radiology2025

Premedication in pediatric Meckel scintigraphy: pantoprazole versus ranitidine for optimizing scan quality.

Hasan Önner, Merve Ni̇da Calderon Tobar, Mehmet Sarıkaya, Fatma Özcan Sıkı, Fari̇se Yılmaz, Muslu Kazim Körez, Gonca Kara Gedi̇k

Abstract readComparative Study
In one paragraph

Article in Pediatric radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hasan ÖnnerSelçuk University, Medical Faculty, Department of Nuclear Medicine, Konya, Türkiye. hasan.onner@selcuk.edu.tr.
Merve Ni̇da Calderon TobarSelçuk University, Medical Faculty, Department of Nuclear Medicine, Konya, Türkiye.
Mehmet SarıkayaSelçuk University, Medical Faculty, Department of Nuclear Medicine, Konya, Türkiye.
Fatma Özcan SıkıSelçuk University, Medical Faculty, Department of Pediatric Surgery, Konya, Türkiye.
Fari̇se YılmazSelçuk University, Medical Faculty, Department of Nuclear Medicine, Konya, Türkiye.
Muslu Kazim KörezSelçuk University, Medical Faculty, Department of Nuclear Medicine, Konya, Türkiye.
Gonca Kara Gedi̇kSelçuk University, Medical Faculty, Department of Nuclear Medicine, Konya, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe standard method for diagnosing Meckel diverticulum and identifying ectopic gastric mucosa is

objectiveAfter the withdrawal of ranitidine, we compared the efficacy of the proton pump inhibitor pantoprazole as an alternative premedication agent for MATERIALS AND

methodsThis study assessed the scan quality of 141 children (aged 1 month to 204 months (median = 84 months)) who underwent Meckel scintigraphy over 10 years at a single institution. Before its withdrawal in December 2020, ranitidine was utilized for premedication, while pantoprazole was used thereafter. Therefore, patients were divided into two premedication groups: ranitidine (n = 88) and pantoprazole (n = 53). A high-quality scan was defined as having no

resultsPremedication with pantoprazole resulted in 47.2% of scans showing no

conclusionThis study demonstrates that pantoprazole is statistically non-inferior to ranitidine regarding scan quality and lesion-to-background activity ratios for Meckel diverticulum detection. Pantoprazole offers a reliable alternative for clinical protocols in the absence of ranitidine.

Indexed as

Meckel DiverticulumPantoprazolePremedicationProton Pump InhibitorsRadionuclide ImagingRanitidineAdolescentChildChild, PreschoolFemaleHistamine H2 AntagonistsHumansInfantInfant, NewbornMaleRadiopharmaceuticalsHistamine H2 AntagonistsPantoprazoleProton Pump InhibitorsRadiopharmaceuticalsRanitidineSodium Pertechnetate Tc 99mEctopic gastric mucosaMeckel diverticulumPantoprazolePediatricRanitidineScintigraphy

Identifiers

PMID40515817
PMCPMC12321688

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.