Evidence map›Paper›PMID 40515796›Full record

ArticleLasers in medical science2025

Harnessing optics and statistics for early detection and prognosis in breast and ovarian cancer.

Munir Akhtar, Ali Haider Karar, Farzana Siddique, Hafeez Ullah, Sohail Akhtar, Ghulam Gilanie, Saeedah Musaed Almutairi, Natavan Karamova, Muhammad Umar Dad, Fatima Javaid

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Article in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Munir AkhtarBiophotonics Imaging Techniques Laboratory, Institute of Physics, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan.
Ali Haider KararBiophotonics Imaging Techniques Laboratory, Institute of Physics, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan.
Farzana SiddiqueDepartment of Physics, Lahore Garrison University, Sector C, DHA Phase 6, Lahore, Pakistan.
Hafeez UllahBiophotonics Imaging Techniques Laboratory, Institute of Physics, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan. hafeezullah@iub.edu.pk.
Sohail AkhtarDepartment of Clinical Oncology, Bahawalpur Institute of Nuclear Medicine and Oncology (BINO), Bahawalpur, Pakistan.
Ghulam GilanieBiophotonics Imaging Techniques Laboratory, Institute of Physics, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan.
Saeedah Musaed AlmutairiDepartment of Botany and Microbiology, College of Science, King Saud University, P.O. 2455, Riyadh 11451, Saudi Arabia.
Natavan KaramovaDepartment of Life Sciences, Western Caspian University, Baku, Azerbaijan.
Muhammad Umar DadSchool of Physics and Electronic Science, East China Normal University, Shanghai 200062, China.
Fatima JavaidDepartment of Mathematics, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan.

Funding

King Saud University ORF-2025-470
6 · The paper itself

Abstract

Environmental factors are responsible for 90% of cancers and breast cancer is the most common cancers occurring worldwide. The 18th most frequent cancer is ovarian cancer and sixth most frequent cancer in the world is liver cancer. Why we have chosen this study. Early prognosis and therapeutic development for cancer is the main goal of this manuscript through optics and Pearson correlation tools. Polarimetry is used to quantify biochemical and characterize tissues, especially for cancer prognosis. Four polarimetric parameters total (diattenuation, depolarization and retardance) and orientation that have elevated values for malignant and low values for benign for both breast cancer and ovarian cancers. Most of blood parameters and components show attenuation for both cancers under Cefexime. Size of WBCs fluctuates between6.1-9.2 (µm) for breast cancer and 6.0-8.5 (µm) for ovarian cancer. WBCs show strong correlation with bilirubin total (r = 0.2829, p = 0.000) and creatinine (r = 0.2384, p = 0.000) for breast cancer, RBCs have positive correlation with SGPT (r = 0.1872, p = 0.022) and T. Bilirubin (r = 0.1585, p = 0.000) for breast cancer. Serum creatinine with RBCs (r = 0.113, p = 0.000) and SGPT only with MCV (r = 0.6814, p = 0.000) show very strong positive correlation for liver cancer. Thus polarimetric properties especially retardance and depolarization can be used for early prognosis / diagnose of cancer.Clinical trial number Not applicable.

Indexed as

Breast NeoplasmsEarly Detection of CancerOvarian NeoplasmsBilirubinFemaleHumansPrognosisBilirubinBilirubin totalCefeximeCreatinineDepolarizationPolarimetryRetardance

Identifiers

PMID40515796

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.