ReviewProbiotics and antimicrobial proteins2026
Direct-fed Microbials (DFM) and Poultry Genomics: A Synergistic Approach to Sustainable Antibiotic Free Farming.
Review in Probiotics and antimicrobial proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Harnessing bacterial power and omics technologies for sustainable plastic waste biodegradation.Biodegradation · 2026Review
- Compound microbial intelligent membrane fermentation reshapes the virome and reduces various resistance genes in duck litter.Frontiers in microbiomes · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Improper usage of antibiotics in poultry production is a great threat to the ecosystem because their residues can enter into the food chain or leach into soil or water systems and increase antibiotic resistance risks. Hence, direct-fed microbials (DFMs) have gained recognition as a sustainable and viable alternative to antibiotics in poultry production, capitalizing on the relationship between microbial genetics, host genomics, and gut microbiota. This review delves into the genetic and host genomic mechanisms through DFMs effects including the enhancement of nutrient metabolism, modulation of gut microbiota and strengthening of the host immunity. The revolution of multi-omics has participated in the identification of probiotic strains with desirable traits and revealed their impact on host gene expression, particularly in genes related to intestinal health, such as tight junction proteins and mucins. Furthermore, the review summarizes the benefits of using DFMs in poultry production, the factors affecting their efficacy and their challenges and limitations. Future research integrating host and microbial genomics, along with precision microbiome engineering, holds promise for maximizing the potential of DFMs in advancing sustainable poultry farming practices.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.