Evidence map›Paper›PMID 40515673›Full record

ArticleVeterinary medicine and science2025

Effects of Different Levels of Dietary Curcumin Nano-Micelles on Nutrient Digestibility, Skeletal Growth Indices, and Faecal Consistency of Suckling Simmental Calves Under Heat Stress Conditions.

Mehdi PiyadehKouhsar, Taghi Ghoorchi, Abdolhakim Toghdory, Mostafa HosseinAbadi, Mostafa Bokharaeian

Abstract read
In one paragraph

Article in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mehdi PiyadehKouhsarDepartment of Animal and Poultry Nutrition, Animal Science Faculty, Gorgan University of Agricultural, Science and Natural Resources, Gorgan, Iran.
Taghi GhoorchiDepartment of Animal and Poultry Nutrition, Animal Science Faculty, Gorgan University of Agricultural, Science and Natural Resources, Gorgan, Iran.
Abdolhakim ToghdoryDepartment of Animal and Poultry Nutrition, Animal Science Faculty, Gorgan University of Agricultural, Science and Natural Resources, Gorgan, Iran.
Mostafa HosseinAbadiDepartment of Animal and Poultry Nutrition, Animal Science Faculty, Gorgan University of Agricultural, Science and Natural Resources, Gorgan, Iran.
Mostafa BokharaeianDepartment of Animal and Poultry Nutrition, Animal Science Faculty, Gorgan University of Agricultural, Science and Natural Resources, Gorgan, Iran.ORCID 0000-0002-6302-2763

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the effects of dietary curcumin nano-micelles (CNM) on growth performance, nutrient digestibility, skeletal development, and faecal consistency in heat-stressed suckling Simmental calves. Thirty-two male calves (10 days old; 43.7 ± 2.5 kg) were randomly assigned to one of four dietary treatments: CTRL (control), T20, T40, and T80, corresponding to 0, 20, 40, and 80 mg of CNM per calf per day, with eight replicates per group. The trial lasted 45 days, including a 7-day adaptation period. CNM supplementation significantly improved growth performance, with average daily gain (ADG) increasing in T40 and T80 groups (0.31 kg/day) compared to CTRL (0.29 kg/day; p = 0.029). Dry matter intake (DMI) was higher in T80 (1.58 kg/day) than CTRL (1.47 kg/day; p = 0.003), while feed conversion ratio was unaffected. Nutrient digestibility was generally unchanged, except for neutral detergent fibre (NDF) digestibility, which showed a quadratic response (p = 0.010), with the lowest value observed in T40 (22.33%). CNM significantly enhanced skeletal growth: body length (p = 0.041), hip height (p < 0.001), heart girth (p = 0.005), abdominal girth (p = 0.025), ankle circumference (p = 0.006), pin bone width (p < 0.001), hip width (p = 0.031), and body depth (p = 0.012) increased notably in T40 and T80 groups over time. Faecal consistency remained stable (p = 0.964), indicating no negative effects on intestinal health over time. These findings demonstrate that CNM supplementation can improve feed intake and promote skeletal development in heat-stressed calves, potentially enhancing resilience under thermal stress. Further research is warranted to optimise CNM dosing for sustainable ruminant production.

Indexed as

CurcuminDigestionHeat-Shock ResponseAnimal FeedAnimal Nutritional Physiological PhenomenaAnimalsAnimals, SucklingCattleDietDietary SupplementsDose-Response Relationship, DrugFecesMaleRandom AllocationCurcumincurcumin nano‐micellesheat stressnutrient digestibilitySimmental calvesskeletal indicators

Identifiers

PMID40515673
PMCPMC12166549

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.