Evidence map›Paper›PMID 40515506›Full record

ArticleAnnals of medicine2025

Mortality of

Daniele Roberto Giacobbe, Silvia Dettori, Vincenzo Di Pilato, Erika Asperges, Lorenzo Ball, Enora Berti, Ola Blennow, Bianca Bruzzone, Laure Calvet, Federico Capra Marzani and 39 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Prophylaxis Regimens forJournal of fungi (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

49 authors.

Daniele Roberto GiacobbeDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.ORCID 0000-0003-2385-1759
Silvia DettoriDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Vincenzo Di PilatoDepartment of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.
Erika AspergesDivision of Infectious Diseases, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Lorenzo BallDivision of Infectious Diseases, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Enora BertiAssistance Publique - Hôpitaux de Paris, DMU Médecine, Service de Médecine Intensive Réanimation, Hôpital Henri Mondor, Hôpitaux Universitaires Henri Mondor, Créteil, France.
Ola BlennowDepartment of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.
Bianca BruzzoneHygiene Unit, San Martino Policlinico Hospital - IRCCS for Oncology and Neurosciences, Genoa, Italy.
Laure CalvetService de Médecine Intensive Réanimation, CHU de Clermont-Ferrand, Clermont-Ferrand, France.
Federico Capra MarzaniServizio di Anestesia e Rianimazione 1, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Antonio CasabellaMicrobiology Unit Laboratory Service, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí (I3PT), Universitat Autònoma de Barcelona, Sabadell, Spain.
Sofia ChoudalyUnité de Glycobiologie Structurale et Fonctionnelle, Lille, France.
Anais DartevelMedical Intensive Care Unit, Grenoble Alpes University Hospital, Grenoble, France.
Gennaro De PascaleDipartimento di scienze dell'emergenza, anestesiologiche e della rianimazione, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Gabriele Di MecoInfectious Diseases Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Melissa FallonPublic Health Wales Mycology Reference Laboratory, PHW Microbiology Cardiff, University Hospital of Wales, Cardiff, UK.
Louis-Marie GalerneauMedical Intensive Care Unit, Grenoble Alpes University Hospital, Grenoble, France.
Miguel GallegoRespiratory Department, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí (I3PT), Universitat Autònoma de Barcelona, Sabadell, Spain.
Mauro GiacominiDepartment of Informatics, Bioengineering, Robotics and System Engineering (DIBRIS), University of Genoa, Genoa, Italy.ORCID 0000-0001-5646-2034
Adolfo González SaezServicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Luise HänselDepartment I of Internal Medicine, Excellence Centre for Medical Mycology (ECMM), University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.
Giancarlo IcardiDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Philipp KoehlerDepartment I of Internal Medicine, Excellence Centre for Medical Mycology (ECMM), University of Cologne, Medical Faculty and University Hospital Cologne, Cologne, Germany.
Katrien LagrouDepartment of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.
Tobias LahmerDepartment of Internal Medicine II, Klinikum Rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany.
Philip Lewis WhitePublic Health Wales Mycology Reference Laboratory, PHW Microbiology Cardiff, University Hospital of Wales, Cardiff, UK.
Laura MagnascoInfectious Diseases Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Anna MarcheseDepartment of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.
Cristina MarelliInfectious Diseases Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.ORCID 0000-0003-1510-1819
Mercedes Marín ArriazaServicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, Spain.ORCID 0000-0001-8639-5215
Ignacio Martin-LoechesDepartment of Intensive Care Medicine, Multidisciplinary Intensive Care Research Organization (MICRO), Leinster, Dublin, Ireland.
Armand Mekontso-DessapAssistance Publique - Hôpitaux de Paris, DMU Médecine, Service de Médecine Intensive Réanimation, Hôpital Henri Mondor, Hôpitaux Universitaires Henri Mondor, Créteil, France.
Malgorzata MikulskaDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Marco MuccioDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Alessandra MularoniUnit of Infectious Diseases, ISMETT-IRCCS Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, Palermo, Italy.
Anna NordlanderDepartment of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.
Julien PoissyUnité de Glycobiologie Structurale et Fonctionnelle, Lille, France.
Giovanna RusselliUnit of Infectious Diseases, ISMETT-IRCCS Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, Palermo, Italy.
Alessio SignoriSection of Biostatistics, Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Carlo TasciniInfectious Diseases Clinic, Azienda Sanitaria Universitaria del Friuli Centrale (ASUFC), Udine, Italy.
Louis-Maxime VaconsinMedical and Infectious Diseases ICU, APHP, Bichat hospital, Paris, France.
Joel VargasDipartimento di scienze dell'emergenza, anestesiologiche e della rianimazione, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Antonio VenaDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Joost WautersDepartment of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.
Paolo PelosiDepartment of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.
Jean-Francois TimsitMedical and Infectious Diseases ICU, APHP, Bichat hospital, Paris, France.
Matteo BassettiDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
JIR-ICU Investigators (Collaborators), the Critically Ill Patients Study Group of the European Society of Clinical Microbiology and Infectious Diseases (ESGCIP), and the Fungal Infections Study Group of the European Society of Clinical Microbiology and Infectious Diseases (EFISG)
JIR-ICU investigators (collaborators)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsThe primary objective of the present post-hoc analysis of a multicenter, multinational, retrospective study was to assess factors impacting prognosis in ICU patients with PJP through univariable and multivariable analyses.

resultsA total of 107 patients were included; 28 had proven PJP (26.2%), and 79 had presumptive PJP (73.8%). The overall 30-day mortality was 52.7% (95% confidence interval [CI] 42.1-62.2). In the multivariable analysis, metastatic solid tumor (hazard ratio [HR] 3.49; 95% CI 1.71-7.13,

conclusionPJP mortality remains high in ICU patients. Conditions other than HIV infection are emerging not only as non-classical risk factors for PJP development, but also as important mortality predictors. A better understanding of the reasons underlying this evolving landscape could be crucial to improve PJP management and survival.

Indexed as

Intensive Care UnitsPneumocystis cariniiPneumonia, PneumocystisAdultAgedFemaleHospital MortalityHumansMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsICUmortalityPCPPJPPneumocystispneumonia

Identifiers

PMID40515506
PMCPMC12168387

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.