Evidence map›Paper›PMID 40515483›Full record

Trial reportThe Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association2025

An exploratory study to understand how rurality status and demographic characteristics are associated with enrollment, engagement, and retention in a digital health intervention targeting the Appalachian region.

Donna-Jean P Brock, Lee M Ritterband, Wen You, Annie L Reid, Kathleen J Porter, Theresa Markwalter, Jamie M Zoellner

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Trial
  3. An exploratory study to understand how rurality status and demographic characteristics are associated with enrollment, engagement, and retention in a digital health intervention targeting the Appalachian region.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025
    Trial
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Donna-Jean P BrockDepartment of Public Health Sciences, School of Medicine, University of Virginia, Charlottesville, Virginia, USA.ORCID https://orcid.org/0000-0002-1338-386X
Lee M RitterbandDepartment of Psychiatry and Neurobehavioral Sciences, School of Medicine, University of Virginia, Charlottesville, Virginia, USA.
Wen YouDepartment of Public Health Sciences, School of Medicine, University of Virginia, Charlottesville, Virginia, USA.
Annie L ReidDepartment of Public Health Sciences, School of Medicine, University of Virginia, Charlottesville, Virginia, USA.
Kathleen J PorterDepartment of Public Health Sciences, School of Medicine, University of Virginia, Charlottesville, Virginia, USA.
Theresa MarkwalterDepartment of Public Health Sciences, School of Medicine, University of Virginia, Charlottesville, Virginia, USA.
Jamie M ZoellnerDepartment of Public Health Sciences, School of Medicine, University of Virginia, Charlottesville, Virginia, USA.ORCID https://orcid.org/0000-0001-5445-5594

Funding

Optimizing iSIPsmarter: A Factorial Trial to Enhance Engagement and Effectiveness on Sugary Beverages and Weight among rural Appalachian adultsR01MD015033 · NIMHD · UNIVERSITY OF VIRGINIA · PI Lee M Ritterband, Jamie Zoellner · 2020 to 2026
$4.2M
National Institutes of Minority Health and Health Disparities R01MD015033NIH HHSNIMHD NIH HHS R01 MD015033
6 · The paper itself

Abstract

purposeDigital health studies exploring group disparities across research phases are limited. As a secondary aim of a larger digital health trial, this study explored how rurality and other sociodemographics were associated with enrollment, retention, and engagement in a randomized controlled sugar-sweetened beverage (SSB) reduction trial.

methodsParticipants from a primarily Appalachian sample were randomized into iSIPsmarter (experimental) or static Patient Education (control) websites. Enrollment, retention (6 months), and iSIPsmarter engagement (completion of metered program Core content and SSB and weight diaries) were collected from July 2021 to August 2023. Regression models assessed subgroup associations using Rural Urban Continuum Codes (RUCC), sex, race, age, income, education, and other sociodemographic predictors.

findingsOf the 509 eligible participants, 249 (49%) enrolled, and 218 (88%) were retained. Participants were predominantly White (89%), college-educated (59%) females (83%) with household incomes <$55,000/year (52%). Rurality varied: RUCC 1-2 (medium-large metro) = 15%, RUCC 3 (small metro) = 45%, and RUCC 4-9 (nonmetro) = 41%. On average, iSIPsmarter participants (n = 127) completed 4.89/6 (SD = 1.69) Cores and 76% (SD = 29%) and 57% (SD = 31%) of SSB and weight diaries. Rurality was a nonsignificant predictor, but higher education and health literacy increased enrollment likelihood by 37% (95% CI = 1.12-1.67) and 23% (95% CI = 1.03-1.47), respectively. Greater education (OR = 1.51, 95% CI = 1.00-2.29), age (OR = 1.04, 95% CI = 1.01-1.07), and income (OR = 1.13, 95% CI = 1.00-1.28) significantly predicted retention. Older age significantly (P<.05) predicted the completion of Cores and diaries.

conclusionsResults suggested rurality was not significantly associated with enrollment, retention, or engagement, though this conclusion warrants caution. Future digital health studies targeting similar populations should consider additional sociodemographic differences.

Indexed as

DemographyRural PopulationAdultAppalachian RegionDigital HealthFemaleHumansMaleMiddle Ageddigital health behavioral interventionsdigital health engagementenrollmenthealth disparitieshealth equityretentionrural health

Identifiers

PMID40515483
PMCPMC12166349

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.