Evidence map›Paper›PMID 40515465›Full record

ArticleASN neuro2025

Analysis of Oligodendrocyte Lineage Cell Progression with Cre-Mediated RiboTag Reporter Lines.

George S Melchor, Maya S Shah, Zeeba Manavi, Lauren M Rosko, Jingwen Hu, Haiyang Wang, Maryna Baydyuk, Jeffrey K Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ASN neuro, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

George S MelchorDepartment of Biology, Georgetown University, Washington, DC, USA.ORCID 0000-0001-5256-3647
Maya S ShahDepartment of Biology, Georgetown University, Washington, DC, USA.
Zeeba ManaviDepartment of Biology, Georgetown University, Washington, DC, USA.
Lauren M RoskoDepartment of Biology, Georgetown University, Washington, DC, USA.
Jingwen HuDepartment of Biology, Georgetown University, Washington, DC, USA.
Haiyang WangDepartment of Biology, Georgetown University, Washington, DC, USA.
Maryna BaydyukDepartment of Biology, Georgetown University, Washington, DC, USA.
Jeffrey K HuangDepartment of Biology, Georgetown University, Washington, DC, USA.ORCID 0000-0003-0996-9451

Funding

Immunoregulation in CNS remyelinationR01NS107523 · NINDS · GEORGETOWN UNIVERSITY · PI HUANG, JEFFREY K · 2018 to 2022
$1.7M
NINDS NIH HHS R01 NS107523
6 · The paper itself

Abstract

Cre-reporter strategies in transgenic mice are widely used to assess the specificity of gene promoter activities, and for fate-mapping studies during development and under injury conditions. The ribosome tagging strategy, RiboTag, is a transgenic approach, in which a hemagglutinin (HA) tag fused to the endogenous ribosomal protein, RPL22, is expressed through the Cre/loxP system. To profile RiboTag reporter expression in oligodendrocyte lineage cells (OLCs), we generated NG2

Indexed as

Cell LineageGenes, ReporterIntegrasesOligodendrogliaAnimalsCell DifferentiationMiceMice, Inbred C57BLMice, TransgenicTamoxifenCre recombinaseIntegrasesTamoxifenLineage tracingoligodendrocyte precursor cellsoligodendrocytesremyelinationRiboTag

Identifiers

PMID40515465
PMCPMC12169044

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.