Evidence map›Paper›PMID 40515425›Full record

ArticleThe Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association2025

Evolution of the US nonmetropolitan mortality disadvantage by sex, state, and year, 1999-2019.

Eugenio Paglino, Irma T Elo, Samuel H Preston, Katherine Hempstead, Andrew C Stokes

Abstract read
In one paragraph

Article in The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Evolution of the US nonmetropolitan mortality disadvantage by sex, state, and year, 1999-2019.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eugenio PaglinoHelsinki Institute for Demography and Population Health, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0001-8733-6460
Irma T EloPopulation Studies Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Samuel H PrestonPopulation Studies Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Katherine HempsteadRobert Wood Johnson Foundation, Princeton, New Jersey, USA.
Andrew C StokesDepartment of Global Health, Boston University School of Public Health, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-8502-3636

Funding

Causes of Geographic Divergence in American Mortality Between 1990 and 2015: Health Behaviors, Health Care Access and MigrationR01AG060115 · NIA · UNIVERSITY OF PENNSYLVANIA · PI ELO, IRMA T. · 2018 to 2022
$1.9M
International Max Planck Research School for Population, Health and Data Science (IMPRS-PHDS)NIA NIH HHS R01 AG060115NIA NIH HHS R01 AG060115-04S1
6 · The paper itself

Abstract

purposeTo examine disparities in nonmetropolitan and metropolitan mortality by state and sex from 1999 to 2019.

methodsWe calculate age-standardized mortality rates for nonmetropolitan and metropolitan areas by state and sex and compute age-standardized differences in these rates within each state and relative to the national average. We further estimate the number of excess deaths in nonmetropolitan areas by state. These are deaths that would have been avoided if nonmetropolitan areas had the same age-specific death rates as metropolitan areas in the same state.

findingsWe document increasing nonmetropolitan mortality disadvantage since 1999 along with significant variation in the magnitude and timing of its emergence by state. Although stagnation in mortality was observed nationally in the mid-2010s, this was not true in all states or in all metropolitan and nonmetropolitan areas. Additionally, mortality trends became progressively more discordant across and within states. Despite this heterogeneity, we document a steady increase in the number of nonmetropolitan excess deaths from 8,400 in 1999 to 47,000 in 2019, representing 9.0% of all nonmetropolitan deaths.

conclusionsNational-level mortality trends mask geographic variation by nonmetropolitan and metropolitan areas within and across states. Further research is needed to identify factors that contribute to these divergent patterns.

Indexed as

Health Status DisparitiesMortalityRural PopulationAdultAgedFemaleHumansMaleMiddle AgedSex FactorsUnited StatesUrban Population

Identifiers

PMID40515425
PMCPMC12166274

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.