ReviewJournal of cosmetic dermatology2025
Hydrogel-Based Therapies for Photoaging: Current Advances and Future Perspectives.
Review in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Intelligent Hydrocolloid-Based Delivery Systems: Innovations in Pharmacy and Cosmetics.Molecules (Basel, Switzerland) · 2026Review
- Supercritical COMaterials today. Bio · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
backgroundPhotoaging, caused by long-term ultraviolet (UV) exposure, leads to wrinkles, loss of skin elasticity, pigmentation disorders, and impaired barrier function due to oxidative stress, DNA damage, and collagen breakdown. Hydrogels, with their high water content (> 90%), biocompatibility, and controlled drug release capabilities, have emerged as a powerful tool for preventing and treating skin photoaging.
aimsTo review current treatment strategies and provide an updated perspective on the treatment of photoaging.
methodsWe searched the PubMed and Web of Science library databases for eligible studies published within the past 5 years, categorizing and evaluating the effects of hydrogels with different carriers and active ingredients.
resultsA total of 21 relevant studies were included, involving Lipid-based Hydrogels, Hyaluronic Acid-based Hydrogels, Chitosan-based Hydrogels, Polyacrylonitrile-modified κ-Carrageenan-based Hydrogels, Gellan Gum/Sodium Alginate-based Hydrogels, Recombinant Collagen-based Hydrogels, and Other Polymer-based Hydrogels.
conclusionsThe collected studies consistently demonstrate that hydrogel therapy is more effective than traditional treatments in reducing UV-induced skin damage and promoting skin repair and regeneration. In addition to improving drug utilization efficiency, hydrogel carriers-particularly those incorporating hyaluronic acid-enhance skin hydration, slow aging, and accelerate wound healing, indicating promising therapeutic potential.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.