Observational studyEuropean journal of medical research2025
Development and external validation of a nomogram for predicting sepsis following flexible ureteroscopy.
Observational study in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The trial behind it
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Who cites it
3 citing papers in PubMed.
- A nomogram estimates postoperative urinary tract infection risk after upper urinary tract stone surgery with double-J stents.Scientific reports · 2026Observational
- Development of a calibrated logistic regression clinical risk score for predicting postoperative sepsis following retrograde intrarenal surgery.World journal of urology · 2026Article
- BMI-stratified nomograms to predict early SIRS-defined sepsis after flexible ureteroscopy.Frontiers in medicine · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFlexible ureteroscopy (FURS) is widely used for the treatment of upper urinary tract stones. However, postoperative sepsis remains a serious complication with potentially life-threatening consequences. This study aimed to develop and externally validate a nomogram for predicting the risk of sepsis following FURS.
methodsA multicenter, retrospective observational cohort study was conducted, involving 1722 patients who underwent FURS. was conducted using data from 1722 patients, with a subset for model development and another for external validation. Key predictive factors such as gender, urine culture results, stone size, staghorn stones, preoperative albumin levels, and operative time were included in the model. Multivariate logistic regression analysis was used to identify independent predictors, and a nomogram was developed.
resultsSix independent predictors were identified: female gender, positive urine culture, stone size ≥ 2 cm, staghorn stones, preoperative albumin levels < 35 g/L, and operative time ≥ 60 min. The nomogram showed excellent performance, with C-index values of 0.88 (training), 0.87 (internal validation), and 0.85 (external validation). The model also demonstrated robust calibration and clinical utility through decision curve analysis.
conclusionThe nomogram developed in this study offers a simple and accurate tool for predicting sepsis risk following FURS. It can aid clinicians in making timely interventions and improving patient outcomes. Further validation and refinement in larger cohorts are needed.
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