Evidence map›Paper›PMID 40514649›Full record

ArticleCardiovascular diabetology2025

Cumulative exposures to glycaemia and lipids are associated with coronary artery disease in type 1 diabetes: a call for action.

Rebecka Bergdal, Valma Harjutsalo, Per-Henrik Groop, Stefan Mutter, FinnDiane Study Group

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Article in Cardiovascular diabetology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rebecka BergdalFolkhälsan Research Center, Biomedicum Helsinki, Helsinki, Finland.ORCID 0009-0000-0225-2947
Valma HarjutsaloFolkhälsan Research Center, Biomedicum Helsinki, Helsinki, Finland.ORCID 0000-0003-3568-9779
Per-Henrik Groop *Folkhälsan Research Center, Biomedicum Helsinki, Helsinki, Finland. per-henrik.groop@helsinki.fi.ORCID 0000-0003-4055-6954
Stefan Mutter *Folkhälsan Research Center, Biomedicum Helsinki, Helsinki, Finland.ORCID 0000-0002-8293-6982
FinnDiane Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHyperglycaemia and dyslipidaemia are well-known risk factors for coronary artery disease (CAD) in type 1 diabetes. The impact of long-term cumulative exposure to these risk factors is less explored. We investigated the relationship between cumulative glycaemic and lipid exposure and CAD in individuals with type 1 diabetes.

methodsThis longitudinal study included 3495 adults with type 1 diabetes from the FinnDiane cohort, without end-stage kidney disease and no history of CAD or stroke at the study baseline. Total cumulative glycaemic exposure (CGE

resultsDuring a median follow-up of 19.38 years, 534 participants had their first-ever CAD event. CGE

conclusionsBoth hyperglycaemia and dyslipidaemia are independently associated with CAD in type 1 diabetes. These findings emphasize the importance of reaching an HbA

Indexed as

Blood GlucoseCoronary Artery DiseaseDiabetes Mellitus, Type 1DyslipidemiasHyperglycemiaLipidsAdultBiomarkersFemaleFinlandGlycated HemoglobinHumansIncidenceLongitudinal StudiesMaleMiddle AgedBiomarkersBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanLipidsCoronary artery diseaseCumulative glycaemic exposureCumulative lipid exposureType 1 diabetes mellitus

Identifiers

PMID40514649
PMCPMC12164207

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.