Evidence map›Paper›PMID 40514637›Full record

ArticleNeurosurgical review2025

Main complications of epilepsy surgery performed in a single center in Latin America.

Irving Fuentes-Calvo, Jimena Gonzalez-Salido, Fernando Sotelo-Díaz, Jimena Colado-Martinez, Irene Gómez-Oropeza, Betsy C Vázquez-Cruz, Fernando Vasquez-Lopez, Luis A Marin-Castañeda, Mario A Sebastián-Díaz, Sergio Moreno-Jiménez and 16 more

Abstract read
In one paragraph

Article in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Irving Fuentes-Calvo *Epilepsy Clinic & Clinical Epileptology Fellowship, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez" & Faculty of Medicine, UNAM, Mexico City, Mexico.ORCID http://orcid.org/0009-0007-0423-636X
Jimena Gonzalez-Salido *Epilepsy Clinic & Clinical Epileptology Fellowship, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez" & Faculty of Medicine, UNAM, Mexico City, Mexico.ORCID http://orcid.org/0000-0001-7357-8442
Fernando Sotelo-DíazNeurosurgery Residency Program, National Institute of Neurology and Neurosurgery, Mexico City, Mexico.
Jimena Colado-MartinezEpilepsy Clinic & Clinical Epileptology Fellowship, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez" & Faculty of Medicine, UNAM, Mexico City, Mexico.
Irene Gómez-OropezaEpilepsy Clinic & Clinical Epileptology Fellowship, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez" & Faculty of Medicine, UNAM, Mexico City, Mexico.
Betsy C Vázquez-CruzEpilepsy Clinic & Clinical Epileptology Fellowship, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez" & Faculty of Medicine, UNAM, Mexico City, Mexico.
Fernando Vasquez-LopezEpilepsy Clinic & Clinical Epileptology Fellowship, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez" & Faculty of Medicine, UNAM, Mexico City, Mexico.
Luis A Marin-CastañedaEpilepsy Clinic & Clinical Epileptology Fellowship, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez" & Faculty of Medicine, UNAM, Mexico City, Mexico.
Mario A Sebastián-DíazNephrology Department, South Central High Specialty Hospital PEMEX, Mexico City, Mexico.
Sergio Moreno-JiménezRadioneurosurgery Unit, National Institute of Neurology and Neurosurgery, Mexico City, Mexico.
Alfonso Arellano-ReynosoFunctional Neurosurgery Department, National Institute of Neurology and Neurosurgery, Mexico City, Mexico.
Guillermo Axayacalt Gutiérrez-AcevesRadioneurosurgery Unit, National Institute of Neurology and Neurosurgery, Mexico City, Mexico.
Salvador Martínez-MedinaNeurology Resident, National Institute of Neurology and Neurosurgery, Mexico City, Mexico.
Santiago Philibert-RosasEpilepsy Clinic & Clinical Epileptology Fellowship, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez" & Faculty of Medicine, UNAM, Mexico City, Mexico.
Oscar Isaac Vázquez-HernándezEpilepsy Clinic & Clinical Epileptology Fellowship, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez" & Faculty of Medicine, UNAM, Mexico City, Mexico.
Juan Carlos Vera-LópezEpilepsy Clinic & Clinical Epileptology Fellowship, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez" & Faculty of Medicine, UNAM, Mexico City, Mexico.
Nahomi M Herrera-NogueraEpilepsy Clinic & Clinical Epileptology Fellowship, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez" & Faculty of Medicine, UNAM, Mexico City, Mexico.
Fernando M Chavez-HassanEpilepsy Department, Hospital Bautista, Managua, Nicaragua.
Juana Villeda-HernandezExperimental Pathology Laboratory, National Institute of Neurology and Neurosurgery, Mexico City, Mexico.
Maximo Leon-VazquezDepartment of Neuroscience, Instituto Mexicano del Seguro Social Centro Médico Nacional "La Raza", Mexico City, Mexico.
Aurelio Jara-PradoGenetics Department, National Institute of Neurology and Neurosurgery, Mexico City, Mexico.
Adriana Ochoa-MoralesGenetics Department, National Institute of Neurology and Neurosurgery, Mexico City, Mexico.
Jorge Guerrero-CamachoGenetics Department, National Institute of Neurology and Neurosurgery, Mexico City, Mexico.
Diego A Barrios-GonzálezGeneral Surgery Residency Program, General Hospital, IMSS., 20 La Margarita, Puebla City, México.
Mario A Alonso-VanegasInternational Epilepsy Center, HMG Coyoacán, Mexico City, Mexico.
Iris E Martínez-JuárezEpilepsy Clinic & Clinical Epileptology Fellowship, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez" & Faculty of Medicine, UNAM, Mexico City, Mexico. imartinez@innn.edu.mx.ORCID http://orcid.org/0000-0001-6512-5312

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDescribe the main medical and neurological complications following epilepsy surgery at a tertiary care center in Latin America. MATERIALS AND

methodsA retrospective study was conducted from 2006 to 2013 at the National Institute of Neurology and Neurosurgery in Mexico City. Patients aged over 18 years with drug-resistant epilepsy who underwent surgery and had a minimum follow-up of one year were included. Statistical analyses performed were Fisher's exact test, Pearson's Chi-square, and one-way ANOVA with Tukey post hoc for multiple comparisons.

resultsOf 204 clinical records reviewed, 165 met inclusion criteria, and 95 (57.6%) underwent epilepsy surgery. Most patients (73.7%) had temporal lobectomy with amygdalohippocampectomy, followed by lesionectomy (9.5%), corpus callosotomy (15.8%), and one (0.6%) vagus nerve stimulator implantation. Minor medical complications occurred in 6.3% of patients, with extracranial infection (4.2%) and CSF fistula (2.1%) being the most common. Minor neurological complications were observed in 29.5%, including cranial nerve deficits (2.1%), intracranial hematoma (2.1%), and quadrantanopia (25.3%). One patient (1.1%) experienced a major complication (hemianopsia).

conclusionThis large LATAM cohort highlights the low complication rate of epilepsy surgery. Early referral of DRE patients demonstrated statistically significant favorable outcomes and fewer postoperative complications. Despite its demonstrated safety when performed by experienced specialists, its underutilization persists due to access barriers, even though untreated epilepsy poses significantly greater risks.

Indexed as

Drug Resistant EpilepsyEpilepsyNeurosurgical ProceduresPostoperative ComplicationsAdolescentAdultFemaleHumansLatin AmericaMaleMiddle AgedRetrospective StudiesTreatment OutcomeYoung AdultEpilepsyEpilepsy surgeryFunctional neurosurgeryLATAMMain complicationsNeurosurgery

Identifiers

PMID40514637
PMCPMC12165962

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.