ArticleSurgical and radiologic anatomy : SRA2025
Involvement of the sinuvertebral nerve in the treatment of chronic low back pain through dorsal root ganglion neurostimulation: an anatomical study.
Article in Surgical and radiologic anatomy : SRA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Anatomy of the basivertebral nerve and its implications in the vertebrogenic pain. Systematic review and mapping of evidence.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- The Sinuvertebral Nerve and Basivertebral Nerve: Analyzing the Central Role of the Vertebral-Disc Unit in Chronic Low Back Pain.Current pain and headache reports · 2026Review
- Neuroregulatory Biomaterials for Intervertebral Disc Regeneration via Neuro-Disc Microenvironment Modulation.Research (Washington, D.C.) · 2026Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveDue to the anatomical proximity of the SVN to the dorsal root ganglion (DRG), several authors have highlighted the potential benefits of DRG stimulation in the management of chronic low back pain. However, the optimal vertebral level for electrode implantation remains debated. To determine the relevance of stimulating the sinuvertebral nerve (SVN) in the management of chronic low back pain and the most appropriate vertebral level for the implantation of this type of electrode.
methodsWe dissected the thoraco-lumbar spine (T12 to L5) of six anatomical specimens to highlight the path, innervation areas, and various branches of the SVN.
resultsWe confirmed that the SVN innervates the posterior third of the intervertebral discs (IVD), the posterior longitudinal ligament (PLL), the anterior face of the dural sheath, the periosteum, the walls of the basivertebral veins, the segmental arteries, and their branches. Moreover, we demonstrated the dual somatic and sympathetic roles of the SVN. Finally, we observed an intra- and intersegmental network covering several adjacent vertebral levels. The superficial network of the SVN converges towards the L2 spinal nerve (SN).
conclusionWe demonstrated the anatomical rationale for stimulating the DRG through rigorous anatomical dissection of the SVN. The most relevant indication appears to be for Persistant Spinal Pain Syndrome (PSPS) type 2 patients, with electrode implantation at the L2 vertebral level bilaterally.
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