Evidence map›Paper›PMID 40514584›Full record

ArticleEmergency radiology2025

Promising initial evaluation: the Shock Thyroid Imaging Score (STIS) could predict mortality in hemodynamically unstable trauma patients.

Matthew C Mueller, Jacques du Plessis, Abdelazim M E Mohammed, Rawan Abu Mughli, Michael E O'Keeffe, Sadia R Qamar, Jason A Robins, Chantelle Q Y Lin, Pascal N Tyrrell, Ferco H Berger

Abstract read
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In one paragraph

Article in Emergency radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Matthew C MuellerEmergency and Trauma Radiology Division, Department of Medical Imaging, Precision Diagnostics and Therapeutics Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.ORCID http://orcid.org/0000-0002-7948-5180
Jacques du PlessisEmergency and Trauma Radiology Division, Department of Medical Imaging, Precision Diagnostics and Therapeutics Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.ORCID http://orcid.org/0000-0002-6399-3113
Abdelazim M E MohammedSouth Tees University Hospital NHS Foundation Trust, Middlesbrough, Cleveland, UK.
Rawan Abu MughliEmergency and Trauma Radiology Division, Department of Medical Imaging, Precision Diagnostics and Therapeutics Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.ORCID http://orcid.org/0000-0002-9494-2925
Michael E O'KeeffeEmergency and Trauma Radiology Division, Department of Medical Imaging, Precision Diagnostics and Therapeutics Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.
Sadia R QamarEmergency and Trauma Radiology Division, Department of Medical Imaging, Precision Diagnostics and Therapeutics Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.ORCID http://orcid.org/0000-0001-6637-6092
Jason A RobinsEmergency and Trauma Radiology Division, Department of Medical Imaging, Precision Diagnostics and Therapeutics Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.
Chantelle Q Y LinDepartment of Medical Imaging, Temerty Faculty of Medicine, University of Toronto, ON, Toronto, Canada.ORCID http://orcid.org/0009-0001-2632-9678
Pascal N TyrrellDepartment of Medical Imaging, Temerty Faculty of Medicine, University of Toronto, ON, Toronto, Canada.ORCID http://orcid.org/0000-0003-2277-3824
Ferco H BergerEmergency and Trauma Radiology Division, Department of Medical Imaging, Precision Diagnostics and Therapeutics Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada. ferco.berger@sunnybrook.ca.ORCID http://orcid.org/0000-0003-3696-2554

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate a newly proposed ‘Shock Thyroid Imaging Score’ (STIS) for predicting mortality in hemodynamically unstable trauma patients and to assess association of STIS with the Hypovolemic Shock Complex (HSC). MATERIALS AND

methodsThis is a retrospective, single-center study of consecutive hemodynamically unstable trauma patients receiving contrast-enhanced CT between January 2016 and September 2018. A STIS was calculated from scored signs of shock thyroid on chest CTs and correlated to well published abdominal CT signs of HSC. Multivariable logistic regression evaluated STIS association with mortality and compared STIS with Glasgow Coma Scale (GCS) and systolic blood pressure (SBP) in predicting mortality.

resultsA total of 748 patients (mean age 47 years ± 22; 554 men) were evaluated. STIS was associated with all abdominal visceral signs of HSC on CT, for example adrenal hyperenhancement in 75% (9/12) for STIS > 3 versus 18% (97/538) for STIS = 0 (P =.001) and with an IVC diameter < 9 mm (58% for STIS > 3 (7/12) versus 17% (93/533) when STIS = 0, P <.001), but not with aortic caliber < 13 mm (0% for STIS > 3 (0/12) versus 2% (13/533) for STIS = 0, P =.180). Multivariable logistic regression modelling demonstrated association of higher STIS with in-hospital mortality (odds ratio (OR), 1.54; P <.001), being a stronger predictor of mortality than lower GCS (OR, 1.19; P <.001) and SBP on arrival (OR, 1.0; P =.006).

conclusionInitial evaluation of the proposed Shock Thyroid Imaging Score (STIS) suggests that it could predict mortality in hemodynamically unstable trauma patients and may be a better early prognosticator than Glasgow Coma Scale and systolic blood pressure. Further validation is needed.

Indexed as

ShockThyroid GlandTomography, X-Ray ComputedWounds and InjuriesAdultContrast MediaFemaleGlasgow Coma ScaleHemodynamicsHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesContrast MediaCTHemodynamic instabilityHypovolemic shockShock thyroidTrauma

Identifiers

PMID40514584

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.