Evidence map›Paper›PMID 40514459›Full record

ReviewAbdominal radiology (New York)2026

PSMA-RADS 2.0: a revised framework for PSMA-targeted imaging interpretation and clinical decision-making.

Arwa Elsamny, Amr Wardeh, Alexandra Panyukova, Kamal Kandel, David Lubin, Refky Nicola

Abstract readReview
PubMed Publisher
In one paragraph

Review in Abdominal radiology (New York), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arwa ElsamnySUNY Upstate Medical University, Syracuse, USA. elsamnya@upstate.edu.
Amr WardehSUNY Upstate Medical University, Syracuse, USA.
Alexandra PanyukovaSUNY Upstate Medical University, Syracuse, USA.
Kamal Kandel
David LubinSUNY Upstate Medical University, Syracuse, USA.
Refky NicolaSUNY Upstate Medical University, Syracuse, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PSMA-RADS version 1, introduced by Rowe et al. in 2017, provides a framework for classifying PSMA-targeted PET scans and individual findings based on their likelihood of representing prostate cancer. The system was optimized for findings outside the prostate and was structured as a five-point scale (Rowe et al., Eur Urol 73:485-487, 2018. https://doi.org/10.1016/j.eururo.2017.10.027 . In 2022, an updated PSMA-RADS version was proposed to refine category definitions, address limitations of the initial version, and enhance its role in guiding clinical decisions. The framework includes both lesion-level and patient-level classifications, offering confidence and probability scores in support of clinical decision-making (Leung et al., EJNMMI Res. https://doi.org/10.1186/S13550-022-00948-1 ). This article aims to explore the changes introduced in the updated scale and evaluate their impact on clinical management. It is intended to inform abdominal and general radiologists about recent developments in PSMA-targeted imaging to support multidisciplinary collaboration and patient care.

Indexed as

Clinical Decision-MakingGlutamate Carboxypeptidase IIPositron-Emission TomographyPositron Emission Tomography Computed TomographyProstatic NeoplasmsAntigens, SurfaceHumansMaleRadiology Information SystemsAntigens, SurfaceFOLH1 protein, humanGlutamate Carboxypeptidase IIbiochemical recurrencemiPSMA scorePSMA PET/CTPSMA RADSSUV thresholdtreatment response evaluation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.