ArticleJACC. Case reports2025
Severe Coronary Vasospasm Complicated by Thyrotoxicosis in Early Pregnancy.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Thyrotoxicosis and the Heart: An Underrecognized Trigger of Acute Coronary Syndromes.Biomedicines · 2025Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough rare, thyrotoxicosis can precipitate anginal symptoms secondary to coronary vasospasm. CASE SUMMARY: A woman presented in early pregnancy with new-onset retrosternal chest pain associated with nausea, vomiting, palpitations, and dyspnea. Further investigations revealed non-ST-segment elevation myocardial infarction secondary to coronary vasospasm owing to thyrotoxicosis. She was managed conservatively to restore euthyroidism with slow resolution of vasospasm. DISCUSSION: Although the link between elevated thyroid hormone and coronary vasospasm is known, its occurrence during pregnancy is not well-documented. Likely a combination of pregnancy physiology, thyrotoxicosis, and coronary anatomical variance contributed to this severe case of coronary vasospasm. We highlight the importance of timely investigations and conservative management strategies during pregnancy. TAKE-HOME MESSAGES: Coronary vasospasm should be considered early for patients with anginal symptoms and a history of hyperthyroidism. Conservative management to restore euthyroidism should be recognized as the standard of care when treating pregnant women with this condition.
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