Evidence map›Paper›PMID 40513303›Full record

ArticleSchizophrenia research2025

The intersection of structural social factors, loneliness, and social activity in individuals with psychotic disorders.

Lauren E McBride, Miya M Gentry, Amy E Pinkham, Eric Granholm, Philip D Harvey, Barton W Palmer, Ellen E Lee, Colin A Depp

Abstract read
In one paragraph

Article in Schizophrenia research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lauren E McBrideSan Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA, USA.
Miya M GentrySan Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA, USA.
Amy E PinkhamSchool of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, TX, USA.
Eric GranholmDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Philip D HarveyUniversity of Miami Miller School of Medicine, Miami, FL, USA; Research Service, Bruce W Cater Miami VA Healthcare System, Miami, FL, USA.
Barton W PalmerDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA; Veterans Affairs San Diego Healthcare System, Mental Illness, Research, Education, and Clinical Center (MIRECC), San Diego, CA, USA.
Ellen E LeeDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA; Veterans Affairs San Diego Healthcare System, Mental Illness, Research, Education, and Clinical Center (MIRECC), San Diego, CA, USA.
Colin A DeppDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA. Electronic address: cdepp@health.ucsd.edu.

Funding

Loneliness in Aging with SchizophreniaR01MH120201 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PALMER, BARTON W. · 2020 to 2024
$3.9M
Social Cognition and Suicide in Psychotic DisordersR01MH116902 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEPP, COLIN A. · 2019 to 2022
$3.2M
Transdiagnostic Reward System Dynamics and Social Disconnection in SuicideR01MH130396 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Colin A. Depp, Charles Taylor · 2023 to 2026
$3.0M
NIMH NIH HHS R01 MH116902NIMH NIH HHS R01 MH120201NIMH NIH HHS R01 MH130396
6 · The paper itself

Abstract

introductionPeople with psychotic disorders are disproportionately lonely, which is associated with negative health outcomes. Structural and subjective factors determine social connectedness, and ecological momentary assessment (EMA) enables simultaneous quantification of social activity. However, how structural factors (e.g., relationship status, living situation) and sociodemographic variables moderate the relationship between social activity and loneliness in psychosis is unknown.

methodsN = 253 participants with a psychotic disorder completed the UCLA Loneliness Scale. Social activity was subsequently measured with EMA smartphone surveys 3×/day for 10 days. We assessed main effects of sociodemographic variables on structural factors, loneliness, and EMA-derived social activity (time alone, in interactions, at home). We then evaluated moderation effects of sociodemographic and structural factors on the relationship between loneliness and social activity.

resultsThere were no main effects of sociodemographic or structural factors on loneliness. Unemployed participants answered more surveys at home. Those who were single, not Latino/a/x/e, and living alone answered more surveys alone. Not interacting with others was linked to having a schizophrenia spectrum disorder (vs. mood disorder with psychosis), being unemployed, being single, and living alone. Associations between loneliness and social activity were modest. Moderator analyses revealed stronger relationships between loneliness, being at home, and not interacting with others for older and financially dependent participants.

conclusionRelationships between loneliness and social activity may vary by structural factors in psychotic disorders. These findings suggest that researchers and clinicians should consider social context when measuring social activity. Interventions targeting social activity may more effectively reduce loneliness in subgroups of psychotic disorders.

Indexed as

LonelinessPsychotic DisordersSchizophreniaSocial InteractionAdultEcological Momentary AssessmentFemaleHumansMaleMiddle AgedSocial FactorsUnemploymentYoung AdultEcological momentary assessmentLonelinessPsychosisSocial connection

Identifiers

PMID40513303
PMCPMC12286742

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.