Evidence map›Paper›PMID 40513052›Full record

ArticleJCO clinical cancer informatics2025

Classifying Stereotactic Radiosurgery Patients by Primary Diagnosis Using Natural Language Processing of Clinical Notes.

Mario Fugal, David Marshall, Alexander V Alekseyenko, Xia Jing, Graham Warren, Jihad Obeid

Abstract read
In one paragraph

Article in JCO clinical cancer informatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Mario FugalMedical University of South Carolina, Charleston, SC.ORCID 0009-0002-2448-0013
David MarshallMedical University of South Carolina, Charleston, SC.
Alexander V AlekseyenkoMedical University of South Carolina, Charleston, SC.
Xia JingClemson University, Clemson, SC.ORCID 0000-0002-1916-4588
Graham WarrenMedical University of South Carolina, Charleston, SC.
Jihad ObeidMedical University of South Carolina, Charleston, SC.ORCID 0000-0002-7193-7779

Funding

The South Carolina Clinical & Translational Research Institute (SCTR)UM1TR005294 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI KATHLEEN T. BRADY, PATRICK A FLUME · 2025 to 2026
$7.6M
NCATS NIH HHS UM1 TR005294
6 · The paper itself

Abstract

purposeAccurate identification of the primary tumor diagnosis of patients who have undergone stereotactic radiosurgery (SRS) from electronic health records is a critical but challenging task. Traditional methods of identifying the primary tumor histology relying on International Classification of Diseases (ICD)9 and ICD10 CM codes often fall short in granularity and completeness, particularly for patients with metastatic cancer.

methodsIn this study, we propose an approach leveraging natural language processing (NLP) algorithms to enhance the accuracy of extracting primary tumor histology from the patient's electronic records.

resultsThrough manual annotation of patient data and subsequent algorithm training, we achieved improvements in accuracy and efficiency in primary tumor type classification and finding histology subtypes not available in ICD10 CM.

conclusionOur findings underscore the value of NLP in refining research processes, identifying patients' cohorts, and improving efficiencies with the goal of potentially improving patient outcomes in SRS treatment.

Indexed as

Electronic Health RecordsNatural Language ProcessingNeoplasmsRadiosurgeryAlgorithmsHumans

Identifiers

PMID40513052
PMCPMC12178166

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.