Evidence map›Paper›PMID 40512930›Full record

ArticleOptics letters2025

Polarimetric coherent anti-Stokes Raman scattering microscopy of collagen.

Lingxiao Yang, Janet E Sorrells, Rishyashring R Iyer, Stephen A Boppart

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Optics letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lingxiao Yang
Janet E Sorrells
Rishyashring R Iyer
Stephen A Boppart

Funding

The Center for Label-free Imagingand Multiscale Biophotonics (CLIMB)P41EB031772 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Stephen A Boppart · 2022 to 2026
$7.6M
Integration of Raman Spectroscopy and Optical Coherence Tomography (RS-OCT) for In-Vivo Identification of Bacterial Otitis MediaR01EB028615 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BOPPART, STEPHEN A, MAHADEVAN-JANSEN, ANITA · 2019 to 2022
$2.5M
Tissue microenvironment (TIMe) training programT32EB019944 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BHARGAVA, ROHIT, GASKINS, REX · 2016 to 2025
$1.9M
NIBIB NIH HHS P41 EB031772NIBIB NIH HHS R01 EB028615NIBIB NIH HHS T32 EB019944
6 · The paper itself

Abstract

We demonstrate polarimetric coherent anti-Stokes Raman scattering (PCARS) microscopy for quantitative analysis of collagen orientation. Using polarization-modulated excitation and cross-polarized detection, we extract both chemical and orientational information from intact tissues. We introduce two complementary analyses: the CARS peak polarization ratio (PPR) and Fourier domain polarimetric analysis, providing a robust characterization of collagen organization. This method enables rapid, label-free imaging of a collagen structure with molecular specificity, offering what we believe to be new capabilities for studying collagen remodeling in biological processes.

Indexed as

CollagenMicroscopySpectrum Analysis, RamanAnimalsCollagen

Identifiers

PMID40512930
PMCPMC12767204

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.