Evidence map›Paper›PMID 40512853›Full record

ArticleScience advances2025

Damage-resistant and body-temperature shape memory skin-mimic elastomer for biomedical applications.

Jiaxin Shi, Fei Xia, Qingchao Tu, Chen Wang, Zhiqi Wang, Bo Li, Baohua Guo, Chong Qiu, Jun Xu

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiaxin ShiAdvanced Materials Laboratory of Ministry of Education (MOE), Department of Chemical Engineering, Tsinghua University, Beijing 100084, China.ORCID 0000-0002-8854-1367
Fei XiaState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Qingchao TuState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Chen WangState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Zhiqi WangAdvanced Materials Laboratory of Ministry of Education (MOE), Department of Chemical Engineering, Tsinghua University, Beijing 100084, China.
Bo LiAdvanced Materials Laboratory of Ministry of Education (MOE), Department of Chemical Engineering, Tsinghua University, Beijing 100084, China.
Baohua GuoAdvanced Materials Laboratory of Ministry of Education (MOE), Department of Chemical Engineering, Tsinghua University, Beijing 100084, China.ORCID 0000-0002-4859-0893
Chong QiuState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.ORCID 0000-0001-6343-5480
Jun XuAdvanced Materials Laboratory of Ministry of Education (MOE), Department of Chemical Engineering, Tsinghua University, Beijing 100084, China.ORCID 0000-0003-2345-0541

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The integration of high strength, super toughness, damage resistance, body-temperature shape memory, and biosafety into a single skin-mimic material system has been a notable challenge in the realm of material science and biomedical applications. In this study, "Lego-like" polyurethane (PU) was selected to amalgamate multiple properties through the design of multilevel structures. By comprehensively designing the chemical and sequence structures of blocks, coordinating weak/strong hydrogen bonds, and achieving rational microphase separation and crystallization, an elastomer was obtained with an exceptional true tensile strength of 1.42 gigapascal, a high fracture energy of 384.7 ± 18.9 kJ/m

Indexed as

Biocompatible MaterialsBiomimetic MaterialsElastomersSkinHumansMaterials TestingPolyurethanesTemperatureTensile StrengthBiocompatible MaterialsElastomersPolyurethanes

Identifiers

PMID40512853
PMCPMC12164989

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.