Evidence map›Paper›PMID 40512660›Full record

ArticleAmerican journal of epidemiology2026

Longitudinal pattern of multimorbidity in older adult population: latent transition analysis in 34 countries.

Ridho Al Izzati, Eduwin Pakpahan

Abstract read
In one paragraph

Article in American journal of epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ridho Al IzzatiApplied Statistics Research Group, School of Engineering, Physics and Mathematics, Northumbria University, Newcastle upon Tyne NE1 8ST, United Kingdom.ORCID 0000-0002-4589-9246
Eduwin PakpahanApplied Statistics Research Group, School of Engineering, Physics and Mathematics, Northumbria University, Newcastle upon Tyne NE1 8ST, United Kingdom.ORCID 0000-0002-0058-1808

Funding

The Mexican Health and Aging Study - IIR01AG018016 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Rebeca Wong · 1999 to 2026
$22.6M
NIA NIH HHS R01 AG018016UKRI Research Studentship
6 · The paper itself

Abstract

Multimorbidity has become a global public health concern, yet cross-national comparisons remain limited, especially in longitudinal settings. This study investigates the longitudinal patterns and transitions of multimorbidity status of people over age 50 in 34 countries. Utilizing comparable health indicators across countries, we examine chronic health conditions (hypertension and diabetes), cognitive function, physical ability, and self-report of general health. Using latent transition analysis, we identify a pattern of multimorbidity and classify it into three classes: mild, moderate, and severe multimorbidity. Mild multimorbidity is characterized by a lower prevalence of 3 morbidities out of 5, while severe multimorbidity is characterized by a higher prevalence across all health conditions. Moderate multimorbidity falls between these 2 extremes. Our findings reveal substantial variation in these classes across countries, with diabetes and hypertension emerging as the predominant condition among older adults with severe and moderate multimorbidity, respectively. Over time, both severe and moderate multimorbidity tend to increase, with similar transition probabilities from mild to more severe categories across countries. Covariate analysis indicates that men and low-educated individuals are more likely to experience severe multimorbidity. These results underscore the importance of understanding multimorbidity patterns and dynamics for effective public health planning and healthcare services. This article is part of a Special Collection on Cross-National Gerontology.

Indexed as

Diabetes MellitusGlobal HealthMultimorbidityAgedAged, 80 and overChronic DiseaseFemaleHumansHypertensionLongitudinal StudiesMaleMiddle AgedPrevalencecross-country comparisonslatent transition analysismultimorbidityolder adults

Identifiers

PMID40512660
PMCPMC13016695

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.