ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2025
Longitudinal development of ocular biometric components and refractive error in children with hyperopic anisometropia.
Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The Changing Natural History of Anisometropia: A Scoping Review.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Anisometropia in children: Current understanding and clinical implications.Taiwan journal of ophthalmologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
purposeTo compare the longitudinal development of spherical equivalent refraction (SER) and ocular biometric components in the more hyperopic (MoreH) and less hyperopic (LessH) eyes of children with hyperopic anisometropia.
methodsThis prospective longitudinal study included 36 children aged 4 to <13 years with hyperopic anisometropia without strabismus. Based on a best-corrected interocular visual acuity difference ≥0.20 logMAR, participants were classified as amblyopic (N = 31) or non-amblyopic (N = 5). SER was derived from cycloplegic refraction and anisometropia was defined as an interocular SER difference ≥1 D. Axial length (AL), anterior chamber depth (ACD), lens thickness (LT), and keratometry (K1, K2) were obtained. Corneal curvature (CR) was calculated and the AL/CR ratio determined. Mean follow-up was 3.7 ± 1.4 years, with 5.8 ± 2.4 visits per child. A linear mixed-effects model estimated the rate of change for SER and the ocular components, comparing the MoreH and LessH eyes.
resultsBaseline anisometropia was 2.66 ± 1.22 D. There were significant differences between the MoreH and LessH eyes for baseline AL, ACD and AL/CR (all p < 0.05). SER change with age was slower for the MoreH than the LessH eyes (-0.11 vs. -0.31 D/year, p < 0.001). The rates of change for AL (0.11 vs. 0.19 mm/year, p < 0.05) and AL/CR (0.01 vs. 0.02, p < 0.001) also were slower for the MoreH eyes. Anisometropia increased with age in the amblyopic subgroup (0.08 D/year) and decreased in the non-amblyopic subgroup (-0.17/D/year; p < 0.001).
conclusionsIn children with hyperopic anisometropia, axial elongation was slower in the MoreH than in the LessH eyes, particularly in those with amblyopia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.