ArticleMikrochimica acta2025
Dynamic SERS substrate based on Au/Ag cascaded PS sphere arrays for sensitive detection of bovine serum albumin and malachite green.
Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
A gap-tunable Au/Ag cascaded polystyrene (PS) sphere array (Au/Ag CPSA) structure, leveraging the thermal expansion properties of polydimethylsiloxane (PDMS) for dynamic nanogap modulation to enhance SERS sensitivity is presented. The nanoarray was fabricated using vacuum thermal evaporation coating followed by chemical reduction. Its morphology was characterized via scanning electron microscopy (FE-SEM), while the electromagnetic field distribution was analyzed using finite difference time domain (FDTD) simulations. Under optimized conditions, the substrate achieved an enhancement factor (EF) of 1.3 × 10⁸ for crystal violet (CV) with a detection limit of 10⁻
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