Evidence map›Paper›PMID 40512363›Full record

ArticleInfection2025

Evaluation of an internet of things device for isothermal molecular detection.

Manfred Weidmann, Jesus Bueno Alvarez, Steffen Zinn, Ruslan Ibragimov, Mohammed Hasani, Elena Graf, Aiko Weber, Frida Arrey, Marcelina Marta Szczygiel, Zuzanna Kowalewska and 5 more

Abstract readEvaluation Study
In one paragraph

Article in Infection, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Point of Care Testing and Recombinase Polymerase Amplification.Journal of clinical laboratory analysis · 2026
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Manfred WeidmannMidge Medical GmbH, Berlin, Germany. manfred_w.weidmann@uni-leipzig.de.
Jesus Bueno AlvarezMidge Medical GmbH, Berlin, Germany.
Steffen ZinnMidge Medical GmbH, Berlin, Germany.
Ruslan IbragimovMidge Medical GmbH, Berlin, Germany.
Mohammed HasaniMidge Medical GmbH, Berlin, Germany.
Elena GrafMidge Medical GmbH, Berlin, Germany.
Aiko WeberMidge Medical GmbH, Berlin, Germany.
Frida ArreyMidge Medical GmbH, Berlin, Germany.
Marcelina Marta SzczygielMidge Medical GmbH, Berlin, Germany.
Zuzanna KowalewskaMidge Medical GmbH, Berlin, Germany.
Rea Maja KobialkaInstitute of Animal Hygiene and Veterinary Public Health, Leipzig University, An den Tierkliniken 43, D-04103, Leipzig, Germany.
Arianna CerutiInstitute of Animal Hygiene and Veterinary Public Health, Leipzig University, An den Tierkliniken 43, D-04103, Leipzig, Germany.
Ahmed Abd El WahedInstitute of Animal Hygiene and Veterinary Public Health, Leipzig University, An den Tierkliniken 43, D-04103, Leipzig, Germany.
Michael DieboldMidge Medical GmbH, Berlin, Germany.
Christian WahnesMidge Medical GmbH, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a low-cost up scalable molecular test platform providing accessibility to frequent testing - the prerequisite to control infectious epidemics. The device uses the Multi-Spectral Digital Sensor AS7341 in a small fluorescence spectrometer which communicates with a Smartphone App via Bluetooth, which passes on the raw data to outsourced computation in the cloud via the internet. This very stable setup allows easy to use on site testing of individual samples and anonymised data analysis while providing the basis for direct result transmission of a rapid isothermal molecular diagnostic test result not only to the user but also to public health bodies. This internet of things (IoT) platform allows to collect real molecular test data from users with usability and industrial up scalability at the heart of the design. The device characteristics are described in detail and the performance for a rapid SARS-CoV-2 Recombinase Polymerase Amplification assay achieved 98.6% sensitivity and 98% specificity testing 148 positive and 501 negative samples.

Indexed as

COVID-19Internet of ThingsMolecular Diagnostic TechniquesNucleic Acid Amplification TechniquesSARS-CoV-2HumansSensitivity and SpecificitySmartphoneHome testInternet of thingsPoint of care testRecombinase polymerase amplificationSARS-CoV-2

Identifiers

PMID40512363
PMCPMC12675774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.