Evidence map›Paper›PMID 40511486›Full record

ArticleThe Medical journal of Australia2025

Health and economic benefits of improving pre-hospital identification of stroke in Australian women: a modelling study.

Thomas Gadsden, Lei Si, Emily R Atkins, Cheryl Carcel, Xia Wang, Stephen Jan, Mark Woodward, Laura E Downey

Abstract read
In one paragraph

Article in The Medical journal of Australia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Thomas GadsdenThe George Institute for Global Health Australia, UNSW Sydney, Sydney, NSW.
Lei SiWestern Sydney University, Sydney, NSW.
Emily R AtkinsThe George Institute for Global Health Australia, UNSW Sydney, Sydney, NSW.
Cheryl CarcelThe George Institute for Global Health Australia, UNSW Sydney, Sydney, NSW.ORCID 0000-0001-8942-953X
Xia WangThe George Institute for Global Health Australia, UNSW Sydney, Sydney, NSW.
Stephen JanThe George Institute for Global Health Australia, UNSW Sydney, Sydney, NSW.
Mark WoodwardThe George Institute for Global Health Australia, UNSW Sydney, Sydney, NSW.
Laura E DowneyThe George Institute for Global Health Australia, UNSW Sydney, Sydney, NSW.

Funding

anonymous philanthropic grant
6 · The paper itself

Abstract

objectiveTo estimate the long term gains in life years and quality-adjusted life years (QALYs) and the cost savings that could be achieved if ischaemic stroke was identified in women with the same level of accuracy received by men, versus the status quo.

designDecision tree and Markov model decision analysis. SETTINGS,

participantsTwo arms including 5513 women aged under 70 years: a hypothetical scenario, in which women receive the same level of accuracy of stroke identification as men (yet experienced symptoms relevant to women); and the status quo. Transitions between post-stroke health states, recurrent stroke and death were made in 1-year cycles over 50 years from a societal perspective.

main outcome measuresYears of life lived, QALYs and costs per patient in the hypothetical scenario relative to the status quo. Results were extrapolated to the national level based on the annual number of ischaemic stroke hospitalisations among women across Australia in the financial year 2020-21.

resultsCompared with the status quo, the hypothetical arm gained 0.14 years of life, gained 0.08 QALYs and saved $2984 per patient. At the national level, for the financial year 2020-21, this equates to 252 life years and 144 QALYs gained, and cost savings of $5.4 million. Outcomes were most sensitive to the probability of an accurate assessment of stroke, short term treatment costs, patient age, and transition probabilities to 90-day post-stroke health states.

conclusionsEnhancing the timely and accurate identification of ischaemic stroke among Australian women in the pre-hospital setting would yield significant health benefits and cost savings to Australian society as a whole.

Indexed as

Emergency Medical ServicesIschemic StrokeStrokeAdultAgedAustraliaCost-Benefit AnalysisDecision TreesFemaleHumansMaleMarkov ChainsMiddle AgedQuality-Adjusted Life Years________________________________________________________________________Healthcare disparitiesHealth services researchStrokeThrombolysis

Identifiers

PMID40511486
PMCPMC12318494

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.