Evidence map›Paper›PMID 40511394›Full record

ArticleBulletin of the World Health Organization2025

Testing indoor residual spraying coverage targets for malaria control, Bioko, Equatorial Guinea.

Guillermo A García, Dianna E B Hergott, David S Galick, Olivier Tresor Donfack, Liberato Motobe Vaz, Lucas O Nze Nchama, Jeremías N Mba Eyono, Restituto M Nguema Avue, Matilde Riloha Rivas, Marcos M Iyanga and 7 more

Abstract read
In one paragraph

Article in Bulletin of the World Health Organization, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Characterization ofInsects · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Guillermo A GarcíaMCD Global Health, 8403 Colesville Road, Silver Spring, MD20910, United States of America (USA).
Dianna E B HergottInstitute for Health Metrics and Evaluation, University of Washington, Seattle, USA.
David S GalickMCD Global Health, Bioko Norte, Equatorial Guinea.
Olivier Tresor DonfackMCD Global Health, Bioko Norte, Equatorial Guinea.
Liberato Motobe VazMCD Global Health, Bioko Norte, Equatorial Guinea.
Lucas O Nze NchamaMCD Global Health, Bioko Norte, Equatorial Guinea.
Jeremías N Mba EyonoMCD Global Health, Bioko Norte, Equatorial Guinea.
Restituto M Nguema AvueMCD Global Health, Bioko Norte, Equatorial Guinea.
Matilde Riloha RivasMinistry of Health and Social Welfare, Bioko Norte, Equatorial Guinea.
Marcos M IyangaMCD Global Health, Bioko Norte, Equatorial Guinea.
Faustino E Ebang BikieMCD Global Health, Bioko Norte, Equatorial Guinea.
Teresa A Ondo MifumuMCD Global Health, Bioko Norte, Equatorial Guinea.
Wonder P PhiriMCD Global Health, Bioko Norte, Equatorial Guinea.
Michael E von FrickenDepartment of Environmental and Global Health, University of Florida, Gainesville, USA.
Robert C ReinerDepartment of Health Metrics Sciences, University of Washington, Seattle, USA.
David L SmithDepartment of Health Metrics Sciences, University of Washington, Seattle, USA.
Carlos A GuerraMCD Global Health, 8403 Colesville Road, Silver Spring, MD20910, United States of America (USA).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To test 50% indoor residual spraying coverage (percentage of households sprayed) for non-inferiority against the recommended 80% coverage for malaria control. Methods: Indoor residual spraying was done in 2021 and 2022 on Bioko, Equatorial Guinea, in a control arm (80% coverage) and intervention arm (50% coverage) with 37 clusters each. We assessed malaria infection in a representative sample of the population during annual surveys using rapid diagnostic tests. We compared the change in the odds of Findings: Relative to baseline, the odds of malaria infection post-intervention were 1.11 (95% confidence interval, CI: 0.81-1.52) in the 80% arm and 0.97 (95% CI: 0.72-1.29) in the 50% arm. In the adjusted model, the change in the odds of Conclusion: There was no evidence that 50% coverage was inferior in preventing malaria, which supports the use of this target in settings where this level makes indoor residual spraying feasible by increasing the cost-effectiveness and equity of the intervention.

Indexed as

InsecticidesMalaria, FalciparumMosquito ControlAdolescentAdultChildChild, PreschoolEquatorial GuineaFemaleHumansMaleInsecticides

Identifiers

PMID40511394
PMCPMC12161160

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.