Evidence map›Paper›PMID 40511353›Full record

ReviewIndian journal of orthopaedics2025

Periarticular Injections for Post-Surgical Analgesia in Shoulder Surgeries: A Systematic Review of Literature and Meta-Analysis.

Thamizhmathi Thangaraju, Girinivasan Chellamuthu, Niranjni Sivadoss, Lakshmi Ramakrishnan, Madhan Jeyaraman

Abstract readReview
In one paragraph

Review in Indian journal of orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Pain Management Strategies in Reverse Total Shoulder Arthroplasty.Current reviews in musculoskeletal medicine · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thamizhmathi ThangarajuDepartment of Anaesthesia and Pain Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu India.
Girinivasan ChellamuthuOrthopaedic Research Group, Coimbatore, Tamil Nadu India.
Niranjni SivadossDepartment of Anaesthesia and Pain Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu India.
Lakshmi RamakrishnanDepartment of Anaesthesia and Pain Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu India.
Madhan JeyaramanDepartment of Orthopaedics, ACS Medical College and Hospital, Dr MGR Educational and Research Institute, Chennai, Tamil Nadu India.ORCID 0000-0002-9045-9493

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Periarticular injections (PAI) are emerging as an effective pain control modality following shoulder surgery. Our objective was to summarize the evidence regarding the effectiveness of PAI in controlling postoperative shoulder pain. Methodology: Comparative studies involving PAI with injections at more than one site in or around the shoulder were included. The comparator was a single-shot regional block or placebo. Databases screened include PubMed, Embase, Scopus, Cochrane, the Web of Science, Clinical Trial Registry-India and Clinical Trials.gov. Results: Eight studies were included in this meta-analysis. Six studies compared PAI with different blocks. Two studies compared the use of PAI as an adjuvant to routine anesthesia. There were 373 patients in the PAI group and 365 patients in the control arm. The mean pain scores in the post-anesthetic care unit were pooled and compared. In the quantitative analysis using a random-effects model, two studies were found to be outliers. In the sensitivity analysis excluding them, the TOST test for equivalence of interventions was significant ( Conclusion: The early results of PAI as a pain control modality after shoulder surgery are comparable to those of conventional blocks. A cocktail of drugs has been used. They are relatively inexpensive and safe. However, larger studies with standardized PAI drugs and protocols are needed to make further recommendations regarding their use.

Indexed as

Pain controlPeriarticular injectionsShoulder surgery

Identifiers

PMID40511353
PMCPMC12151955

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.