Evidence map›Paper›PMID 40511194›Full record

ReviewJournal of pharmacy & bioallied sciences2025

Study of Glutathione S-Transferase, Its Isoenzyme (Pi), and Tumor Markers (CA15-3, HE4) in Breast Carcinoma Patients (Before and After Treatment).

Dattu Hawale, Leela Abichandani, Ranjit Ambad

Abstract readReview
In one paragraph

Review in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dattu HawaleDepartment of Biochemistry, Datta Meghe Medical College, Nagpur, Datta Meghe Institute of Higher Education and Research (DU) Sawangi Wardha, Maharashtra, India.
Leela AbichandaniDepartment of Biochemistry, Datta Meghe Medical College, Nagpur, Datta Meghe Institute of Higher Education and Research (DU) Sawangi Wardha, Maharashtra, India.
Ranjit AmbadDepartment of Biochemistry, Jawaharlal Nehru Medical College, Wardha, Datta Meghe Institute of Higher Education and Research (DU) Sawangi Wardha, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is a leading cause of morbidity and mortality among women globally. Tumor markers play a critical role in diagnosis, treatment monitoring, and prognosis. This review focuses on Glutathione S-transferase (GST), particularly its pi isoenzyme (GSTP1), as well as tumor markers CA15-3 and HE4, in breast cancer patients before and after treatment. These markers are crucial for understanding disease progression, assessing treatment efficacy, and developing therapeutic strategies. Glutathione S-transferase, particularly its pi isoenzyme, along with tumor markers CA15-3 and HE4, holds significant promise in the management of breast cancer. Their combined evaluation before and after treatment could provide crucial insights into disease progression, treatment response, and potential recurrence.

Indexed as

Breast cancer biomarkersglutathione S-transferase (GST)triple-negative breast cancer (TNBC)tumor marker CA15-3tumor marker HE4

Identifiers

PMID40511194
PMCPMC12156632

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.