Evidence map›Paper›PMID 40511136›Full record

ArticleJournal of pharmacy & bioallied sciences2025

Genetic Markers as Predictors of Prognosis and Treatment Response in Patients with Oral Cancer: A Prospective Study.

P Rishal Mohammed, Mitali Dash, Seema Pati, Ashfaq Yaqoob, Sailaja Sanda, Anish Nelson, Heena D Tiwari

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In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

P Rishal MohammedCollege of Dental Medicine, Qatar University, Doha, Qatar.
Mitali DashDepartment of Pathology, S. C. B. Medical College, Cuttack, Odisha, India.
Seema PatiDepartment of ENT, Military Hospital, Kamptee, Nagpur, Maharashtra, India.
Ashfaq YaqoobDepartment of Prosthodontics, College of Dentistry King Khalid University Abha Saudi Arabia.
Sailaja SandaGeneral Dentistry, Government Dental College, Kadapa, Andra Pradesh, India.
Anish NelsonDepartment of Oral and Maxillofacial Surgery, AB Shetty Memorial Institute of Dental Sciences (ABSMIDS), Nitte (Deemed To Be University), Mangalore, Karnataka, India.
Heena D TiwariCommissionerate of Health and Family Welfare, Government of Telangana, Hyderabad, Telangana, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: "Oral squamous cell carcinoma (OSCC)" is a prevalent malignancy globally, with significant morbidity and mortality. Genetic markers are emerging as vital tools in predicting prognosis and treatment responses. This research explores genetic markers' role in OSCC prognosis and therapeutic outcomes. Methods: This prospective research analyzed 150 OSCC patients, investigating the prognostic value of three genetic markers: TP53 mutations, miR-31 expression, and "mismatch repair (MMR)" protein loss. Results: Patients with TP53 mutations exhibited lower survival rates ( Conclusion: Genetic markers, like TP53 mutations, miR-31, and MMR loss, can effectively predict prognosis and treatment responses in OSCC. Integrating these markers into clinical practice can enhance personalized treatment strategies.

Indexed as

miR-31MMRoral squamous cell carcinomaprognosisTP53

Identifiers

PMID40511136
PMCPMC12156516

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.