ArticleJournal of pharmacy & bioallied sciences2025
Nonsurgical vs. Surgical Treatment of Endo-Perio Lesions in Diabetic Patients: A 10-Year Retrospective Cohort Study.
Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Background: Endo-perio lesions are challenging to manage in diabetic patients due to impaired healing and infection risk. This study compared long-term outcomes of nonsurgical and surgical treatments for these lesions. Methods: We analyzed 187 diabetic patients with endo-perio lesions. 92 received nonsurgical treatment (root canal treatment ± scaling and root planing) and 95 underwent surgery (apicoectomy ± guided tissue regeneration). The primary outcome was tooth retention (Kaplan-Meier analysis). Secondary outcomes included lesion resolution, probing depth reduction, clinical attachment level gain, and patient-reported pain/discomfort. Results: At 10 years, tooth retention was 82% (nonsurgical) and 75% (surgical) ( Conclusions: Both approaches showed comparable long-term tooth retention. Surgical treatment enhanced periodontal healing but caused more initial discomfort.
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